MAR 19, 2015 03:00 PM PDT

Early Days of the NIH BRAIN initiative

Presented At Neuroscience
  • Director, National Institute of Neurological Disorders and Stroke
      Dr. Koroshetz was named Acting Director of NINDS in October, 2014.  Prior to this appointment, he served as Deputy Director of NINDS since January, 2007, where he worked with the NINDS Director in program planning and budgeting, and overseeing Institute scientific and administrative functions.
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      <br />Before joining NINDS, Dr. Koroshetz served as vice chair of the neurology service and director of stroke and neurointensive care services at Massachusetts General Hospital (MGH). He was also a professor of neurology at Harvard Medical School and has led neurology resident training at MGH since 1990.
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      <br />A native of Brooklyn, New York, Dr. Koroshetz graduated from Georgetown University and received his medical degree from the University of Chicago. He trained in internal medicine at the University of Chicago and Massachusetts General Hospital. Dr. Koroshetz trained in neurology at MGH, after which he did post-doctoral studies in cellular neurophysiology at MGH and the Harvard neurobiology department. He joined the neurology staff, first in the Huntingtons Disease unit and then in the stroke and neurointensive care service.
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      <br />As a member of the NINDS intramural review and oversight committees, Dr. Koroshetz has been involved in various NINDS symposia and clinical trials, and served as the Institutes representative to the American Neurological Associations Career Development Symposium. He was a member of the NINDS-chaired Brain Attack Coalition (BAC), a group of professional, voluntary and governmental entities dedicated to reducing the occurrence, disabilities, and death associated with stroke.
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    The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the components of brain circuits, i.e., a cell census; 2) developing and testing tools for recording high density information on circuit structure, activity, and manipulating circuit activity; 3) novel technology for noninvasive interrogation and manipulation of circuit activity (next generation imaging). The BRAIN oversight committee provides guidance to NIH as we move forward to engage scientists from computation and physical sciences as well as neuroethics in this historic undertaking. BRAIN is poised to develop the neurotechnologies that enable exploration of the neural basis of human behavior as well as the circuit dysfunction that underlies the disability of neuro/mental/substance abuse disorders.

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