In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as well as cytological and liquid biopsy specimens by NGS is now a key tool. This presentation will cover the role of NGS in a molecular pathology laboratory for the identification of relevant mutations in solid tumors. In particular, the workflow of the new Genexus sequencer and how it may improve on current limitations of NGS in will be discussed in detail.
1. Understand NGS workflow in molecular profiling of tumor samples
2. Be able to identify current and future technologies used in molecular profiling