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    Histone Modification

    A histone modification is a covalent post-translational modification (PTM) to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. The PTMs made to histones can impact gene expression by altering chromatin structure or recruiting histone modifiers. Histone proteins act to package DNA, which wraps around the eight histones, into chromosomes. Histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair.

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    Trending News

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    DEC 10, 2020
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    DEC 10, 2020
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    DEC 09, 2020
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    Webinars

    • OCT 29, 2020 6:00 AM PDT
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    High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
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    Presented at: xMAP® Connect Virtual Conference
    MAY 03, 2018 11:00 AM PDT
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    JAN 17, 2017 8:00 AM PST
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    Presented at: Abcam virtual exhibition: support and products to advance your research
    NOV 23, 2016 8:00 AM PST
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    9:00 AM PT, 11:00 AM CT, 12:00 PM ET Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
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