Histone Modification
A histone modification is a covalent post-translational modification (PTM) to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. The PTMs made to histones can impact gene expression by altering chromatin structure or recruiting histone modifiers. Histone proteins act to package DNA, which wraps around the eight histones, into chromosomes. Histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair.
What's Popular in Histone Modification
MAY 03, 2018
11:00 AM PDT
MAY 03, 2018
11:00 AM PDT
DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
OCT 12, 2017
1:30 PM PDT
OCT 12, 2017
1:30 PM PDT
The deposition and removal of DNA and histone modifications depends on the availability of specific metabolites, suggesting that cellular metabolic pathways may dynamically regulate chromatin...
JAN 17, 2017
8:00 AM PST
JAN 17, 2017
8:00 AM PST
Bivalent domains are thought to be controversial, yet crucial, regulatory hubs in the differentiation of stem cells. Listen in as Dr Philipp Voigt of the Wellcome Trust Centre for...
NOV 23, 2016
8:00 AM PST
NOV 23, 2016
8:00 AM PST
DATE: November 23rd, 2016
TIME: 8:00AM PT, 11:00AM ET
The structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
APR 11, 2016
9:00 AM PDT
APR 11, 2016
9:00 AM PDT
9:00 AM PT, 11:00 AM CT, 12:00 PM ET
Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
