Assistant Professor in the Department of Pathology, Research Scientist, Memorial Sloan-Kettering Cancer CenterBiography
Michael Berger, PhD is an Assistant Attending in the Department of Pathology and an Affiliate Member of the Human Oncology and Pathogenesis Program, with expertise in cancer genomics and computational biology. His research focuses on the enumeration of the spectrum of genetic mutations in human tumors in order to identify biomarkers of cancer progression and drug response. Dr. Berger joined the MSKCC faculty in October 2010 after working as a research scientist and computational biologist in the Cancer Program at the Broad Institute of Harvard and MIT. At the Broad, he served as the project leader and primary data analyst for numerous efforts employing massively parallel "next generation" sequencing to characterize genetic mutations in a range of cancers. He now runs an independent research laboratory at MSKCC that is developing methods to reliably and accurately profile clinical specimens for cancer-related DNA mutations and copy number alterations. His laboratory is engaged in many collaborations with clinical and translational investigators to discover significant oncogenic mutations in rare or understudied tumor types and identify genomic biomarkers exhibiting correlations with clinical outcomes and therapeutic response. He is also working closely with the CLIA compliant Diagnostic Molecular Pathology Laboratory to build a robust profiling pipeline and analytical framework for use in real-time patient management. Dr. Berger received his Bachelor's Degree in Physics at Princeton University and his Ph.D. in Biophysics at Harvard University.