Immunoassay Serology Treponemal Screen

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  • Manager, Scientific Affairs - Infectious Disease with DiaSorin, Inc.
      Dr. Tiffany MacKenzie is the Scientific Affairs Manager focusing on Infectious Disease at DiaSorin, Inc. She came to DiaSorin with 10+ years of laboratory experience: 3 years as an undergraduate research associate during her undergrad career at University of Wisconsin-Madison studying Molecular Biology, 3 years in Research and Development at the start-up company Access Genetics, LLC in Eden Prairie, MN developing HSV multiplex PCR assays and 4.5 years working toward her PhD in Pharmacology at the University of Minnesota-Twin Cities. She joined DiaSorin in Sept of last year (2013) shortly after completing her PhD.


    Serology testing continues to be an indispensable tool for the management of several disease states, especially treponemal screening to monitor syphilis infection in the US. Come to this educational seminar to learn about key objectives in treponemal screening:

    • Discuss CDC Guidelines on treponemal screening: the necessity to perform two independent laboratory syphilis tests to confirm diagnosis
    • Describe diagnostic methods for diagnosing syphilis infection: the order in which they are performed impacts interpretation of results
    • Describe the benefits of screening with a treponema-specific IgG/IgM assay, followed by a non-treponemal test for confirmation: the "Reverse Sequence" algorithm

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