MAY 30, 2019 6:00 AM PDT

Improved Cancer Tracking Through Precision Quantification of Circulating Nucleic Acid Biomarkers

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Chief Scientific Officer, COMBiNATi
    Biography
      Megan Dueck earned her Master of Science degree from UC San Diego in Molecular Pathology in 2005 and completed her PhD in Biological Sciences at UC San Diego in August 2016. From 2005 until 2011, she was a lecturer in the UC Berkeley Bioengineering department receiving awards and NSF funding to develop undergrad curriculum interfacing molecular biology with microfluidics. Megan has over 15 years of experience with microfluidic device and assay design. Currently Megan is a co-founder and CSO for an SF Bay Area biotech hardware company working to bring a revolutionary digital PCR platform to market.

    Abstract

    Oncologists have many options when tasked with treating a patient’s cancer. Unfortunately, many cancer drugs and therapies come with potentially debilitating side effects. As such, it is essential that a doctor track a patient’s response to therapy and change course as early as possible if the therapy is not effective at eradicating cancer cells.  Precision, personalized tracking of cancer burden is also critical for monitoring patients in remission so that therapy can be restarted the moment the cancer resurfaces.  Digital PCR offers clinicians the necessary tool for absolute quantification and precision tracking of circulating DNA cancer biomarkers. COMBiNATi has developed a novel digital PCR platform consisting of a micro-molded plastic consumable and fully integrated instrument designed to address the specific needs of a routine clinical diagnostic tool.  Using a patient-specific assay we have proven the platform’s ability to precisely track a specific cancer patient’s response to therapy and ultimate transition to complete molecular remission. 

    Learning Objectives: 

    1. What is meant by "liquid biopsy", "precision cancer monitoring" and "personalized medicine"?  
    2. What is digital PCR and how can it be used to track a patient's response to therapy or recurrence?
     


    Show Resources
    You May Also Like
    APR 07, 2020 8:00 AM PDT
    C.E. CREDITS
    APR 07, 2020 8:00 AM PDT
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    FEB 26, 2020 9:00 AM PST
    C.E. CREDITS
    FEB 26, 2020 9:00 AM PST
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    MAY 08, 2020 10:00 AM PDT
    C.E. CREDITS
    MAY 08, 2020 10:00 AM PDT
    DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
    JUN 17, 2020 1:30 PM PDT
    C.E. CREDITS
    JUN 17, 2020 1:30 PM PDT
    Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
    FEB 19, 2020 11:00 AM PST
    C.E. CREDITS
    FEB 19, 2020 11:00 AM PST
    DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
    MAR 03, 2020 9:00 AM PST
    C.E. CREDITS
    MAR 03, 2020 9:00 AM PST
    DATE: March 3, 2020 TIME: 9:00am PT, 12:00pm ET Despite the advances of new drugs and the lowering of carbapenem breakpoints to enhance detection of CRE, there should be no complacency about...
    Loading Comments...
    Show Resources