Professor of Genetics, Director of the Center for Computational Genetics, Harvard Medical SchoolBiography
Professor of Genetics, Harvard Medical School, Director of the Center for Computational Genetics. 1984 Harvard PhD included the first direct genomic sequencing method, molecular multiplexing tags, which lead to automation & software used at Genome Therapeutics Corp. for the first commercial genome sequence -- pathogen, Helicobacter in 1994. This multiplex solid-phase sequencing evolved into polonies (1999), ABI-SOLiD (2005) & open-source Polonator.org (2007). Innovations in DNA reading, writing & allele replacement in cells lead to current research & commercialization in human genomics (Complete Genomics, PersonalGenomes.org, 23andme, Knome) , synthetic biology (SynBERC, Joule, LS9) & new ethics/security strategies.