MAY 08, 2019 7:30 AM PDT

Keynote Presentation: Interpreting the Zero $ Genome via Base Editing, Organoids & in Situ Omics

C.E. Credits: CEU
Speaker

Abstract

To interpret genome sequence from telomere to telomere, it is helpful  end-to-end haplotypes with single-molecule epigenetics overlays, via in situ omics at sub-cellular (20 nm) resolution and multicellular (connectome) context.  To test putative causative alleles and therapies, we need faithfully representative organoids and accurate editing of these (not merely NHEJ knockouts).   We also benefit from comprehensive precision medicine datasets on individuals broadly shareable by virtue of either "open consent" protocols (personalgenomes.org) or provably secure queries via homomorphic encryption and blockchain (Nebula.org).  This goals are aided by recent  reduction in cost of human and environmental DNA sequencing by over 10 million fold and new editing tools capable of over 26,000 edits per cell (including tools to read, alter and test changes in DNA repeats).

Learning Objectives: 

1. New technologies -- In situ & Nanopore sequencing are moving us toward portable, real-time, inexpensive (0-$999) & gap-less clinical-grade genomes.
2. Interpretation benefits from testing variants in organoids & large shareable cohorts – enabled by either open consent or secure via homomorphic encryption queries & blockchain public ledgers. 


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MAY 08, 2019 7:30 AM PDT

Keynote Presentation: Interpreting the Zero $ Genome via Base Editing, Organoids & in Situ Omics

C.E. Credits: CEU

Specialty

Genetics

Molecular Diagnostics

Biochemistry

Immunology

Cancer Research

Cancer Diagnostics

Clinical Diagnostics

Microbiology

Gene Sequencing

Molecular Biology

Dna Sequencing

Genomics

Oncology

Gene Expression

Dna

Geography

North America60%

Asia20%

Europe20%

Registration Source

Website Visitors100%

Job Title

Medical Laboratory Technician50%

Student25%

Research Scientist13%

Scientist13%

Organization

Hospital20%

Research Institute20%

Clinical Laboratory20%

Medical School10%

Contract Research Organization (Cro)10%

Manufacturer - Other10%

Academic Institution10%


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