SEP 12, 2019 7:30 AM PDT

Keynote Presentation: Microbial Centric Aging: A Paradigm Shift

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Professor Emeritus, WVU School of Medicine Certified, "High Complexity Clinical Laboratory Director" (HCLD)(ABB)
    Biography
      Professor Emeritus John G. Thomas, PhD, is recognized as an "International Educator and Global Microbiologist " (www.globalbugs.com) having lectured in more than 43 countries while a clinical microbiologist in pathology (Professor), dentistry (Clinical Professor) and Graduate School Education (Adjunct Professor) for 54 years , his translational research emphasizing biofilms and medical devices. He has focused upon micro 3-D- bio Printing of contour fitting gauzes using bio-plastics and unique Prebiotics with Therapeutic Bacteria (Beneficial Bacteria) for chronic wound intervention (SMarT Gauze); this integrates a common pathway, visualized through his 'Microbial Clock' and recently created Center of Hologenomic Clinical Studies (www.globalbugs.com/Hologenomic Center) which underscores a "Dual Citizenship" and co evolution of symbiotic microbes and human ecosystems. "MICROBES MATTER". His Probiotic Solutions integrates Computer Decision Support for Probiotic (Beneficial Bacteria) Guidelines combining AI, Artificial Intelligence and Precision Medicine, expanded recently to emphasize Aging, hypothesized now as a disease by the NIH. He has over 50 publications, multiple book chapters and significant grant support. His military obligation (1969-71)(wounds) and his sabbatical at Cardiff University, Wales, UK (2007)(oral health, biofilms) have remained a driving catalyst. He has been a member of the American Dental Association Scientific Advisory Committee for 8 years and American Society of Microbiology for 54 years. As Faculty at 3 national (Northeastern Ohio Universities College of Medicine, Rutgers University and West Virginia University) and 2 international Universities ( National University of Singapore and Cardiff University) during his career , he has received multiple Alumni and University awards for research and Student Mentoring ; retiring from West Virginia University in 2013 after 23 years as Professor Emeritus , he presently is expanding his research/teaching utilizing the advanced resources of the Allegheny Health Network (Center of Excellence in Biofilm Research) and Carnegie -Mellon University, Pittsburg, PA, and Mass. Gen. Hospital (Dept. of Anesthesia and Critical Care) with Harvard University, Boston, MA, all under the umbrella of his Global Microbiology Consulting. (GMC) (www.globalbugs.com). He was Acting Director of Microbiology, Laboratory Medicine, Allegheny General Hospital, Pittsburgh, PA, 2013-2016.

    Abstract

    Recent molecular advances have unmasked key functions of our microbial kin, our microbiota, and its significant role in our disease and heath, our wellness.  None has matched the interest of the GUT microbiota and its co- functionality with the brain, defining an interplay maximized in  costly age related diseases. The Europeans redefined aging as a disease in 2015, the US via the NIH shortly thereafter in 2016.  Not without controversy, but all highlighting the incredible importance of a balanced, healthy microbiota in aging via the Hologenomic Theory (www.globalbugs.com/Aging and Hologenomic Center) , as Dual Citizens,  birth to death, the loss of microbes,  including fungi,  key in redefining this pathologic process. As of 2035, greater than half of the worlds’ population will be over 65.

    Here, we will highlight this interplay using  2 clocks, the first our 4 quadrant  Microbial Clock (Microbes), followed by the Biologic clock (Humans), both contributing to a common pathway for  metabolic diseases,  immune-scenesence a common pathway. Six brain associated diseases will be a focus via the Gut Brain Axis, catalyzing key mechanisms  of aging, longevity, and “turning back the clock”.  Is it possible?  Dexter, the Dual Faced  Germ-man Puppet (www.globalbugs.com/Teaching with Puppets) will illustrate the importance of both macro (Humans) and micro (microbes)  Holobionts, now defined by available genetic tools and machine learning, creating a Personal Signature.

    Finally, we will discuss intervention of brain functionality via banking terms recognizing the similarities of investment banking and the use of pre/probiotics and diet as mechanisms of leveraging and rejuvenating your microbiome and wellness. Microbial Based Economics (MBE). The GUT is  our banking investment manager and key in creating a balanced microbial portfolio, particularly in age related diseases.
    (www.globalbugs.com/Probiotic Solutions) How should you invest, when and for how long and is precision medicine the key to maximizing microbial wellness.  Ultimately is “Aging longer, well, thru microbiology ‘ possible?  

    Learning Objectives.

    1. Unmask the growing awareness of our microbiota in  wellness and disease, implemented via  a common pathway, most noticeably on brain  functionality, highlighting aging as a reclassified  disease.

    2. Promote the concept of Microbial Banking with Microbial Based Economics, catalyzing the importance  of the GUT microbiota as our investment banker in aging , promoting a lifelong beneficial microbial portfolio, potentially  reconstructed and rejuvenated by precision medicine via synbiotics and or diet.   

     


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