Director, Max Planck Institute for Molecular Genetics
BIOGRAPHY
NOV 09, 2017 2:00 AM PST
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Mammalian DNA methylation landscapes and human cancers
Presented at:
5th annual 24 Hours of Stem Cells™ virtual event
Speaker
Abstract
Concerted efforts over past decades have established a thorough understanding of the canonical somatic DNA methylation landscape as well as its systematic misregulation across many cancers. However, the underlying mechanisms that may direct this genome-scale transformation remains elusive, with no clear model for its acquisition or understanding of its potential developmental utility. I will first summarize work from the past decade that provided key insights into our general understanding of DNA methylation and then discuss recent data that provide evidence for a developmental origin of the shared, erratic cancer methylome.
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NOV 09, 2017 2:00 AM PST
Share
Mammalian DNA methylation landscapes and human cancers
Presented at:
5th annual 24 Hours of Stem Cells™ virtual event
Specialty
Molecular Biology
Biotechnology
Cancer Research
Cell Biology
Genetics
Biomarkers
Genomics
Molecular Diagnostics
Cell Culture
Dna
Biochemistry
Cancer Diagnostics
Immunology
Clinical Diagnostics
Laboratory Testing
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