Mapping Proteomics in Blood: The Human Disease Blood Atlas of Health, Disease, and Aging

This webinar offers a unique opportunity to hear directly from María Bueno Álvez, a core member of the Human Protein Atlas team and first author of the recent Science publication introducing the Human Disease Blood Atlas—a milestone achievement in large-scale proteomics. Built on extensive proteomic and clinical data, this landmark resource maps how thousands of plasma proteins vary across 59 diseases, aging, and health states.

As a rising scientist in the field, María will share the scientific concepts, analytical approaches, and discoveries behind this effort. Participants will also gain first-hand insights from the Human Protein Atlas team on how they leveraged Olink® Explore HT, a high-throughput NGS-based proteomics platform, to quantify more than 5,000 plasma proteins across over 8,000 individuals.

This large-scale profiling effort delivers unprecedented resolution into how protein signatures shift across disease and the human lifespan—establishing a new foundation for precision medicine and translational biomarker research.

Learning objectives:

• Gain insight into the conceptual framework and experimental design that enabled the creation of the pan-disease Human Disease Blood Atlas.
• Discover the translational potential of this resource for biomarker discovery, early disease detection, and personalized health monitoring.
• Understand current limitations, future challenges, and how the scientific community can build upon this foundational atlas to advance precision medicine.