SEP 30, 2020 9:00 AM PDT

Massively parallel microbial genome engineering using the Onyx™ Platform

Presented at: CRISPR 2020
Sponsored by: Inscripta
C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • VP Applications Development, Inscripta
    Biography

      Nandini Krishnamurthy leads the Microbial Applications Development team at Inscripta.  She brings greater than 15 years of research and development experience leading at the interface of experimental and computational biology. Most recently she served as Senior Research Manager, at Corteva Agriscience responsible for delivering innovative solutions in diverse trait areas using genome editing technology in multiple crops to drive differential advantage in the market. Prior to this, she has served in various positions at DuPont Pioneer, Genentech, the University of California, Berkeley, and Rockefeller University. Nandini holds a PhD in Plant Biology from Texas A&M University.


    Abstract

    While transformative, first-generation CRISPR technologies remain limited across multiple important dimensions including scalability, editing efficiency, types of modifications available, and ease of use. Inscripta’s Onyx™ platform addresses these limitations by offering push-button, high efficiency, massively parallel, and precise delivery of diverse edit types across the genomes of S. cerevisiae and E. coli. The platform simplifies previously complex CRISPR strain engineering workflows by offering an end-to-end solution from design through engineered strain library and analytics, including software, reagents and a benchtop instrument. Join us to learn more about this platform and see examples of engineering genomes at unprecedented scale end efficiency.

    Learning Objectives:

    1. Introduction to Inscripta’s Onyx™ Digital Genome Engineering Platform

    2. Examples of  genome-wide strain engineering application in E. coli and S. cerevisiae


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