Measuring What Matters: Proliferation and Cell Death Biomarkers for Oncology Research

C.E. Credits: P.A.C.E. CE Florida CE
Speakers
  • Commercial Business Development Manager, Diapharma Group, Inc.
    Biography
      Olivia Stricker earned her PhD from the University of Cincinnati, where she focused much of her time working in cell signaling and immunology assays. After graduating, she left the bench to work for a recombinant protein manufacturer and ultimately acted as their Chief Scientific Officer. In her position there, she explored the needs of the stem cell and immunology markets for purified cytokines, chemokines and growth factors. Now, at Diapharma, Olivia is heading up business development and is working to help commercialize unique biomarkers in the US market. She enjoys Jazzercise, weekend baking and long walks on the beach.

    Abstract:

    Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications.  Cancer is fundamentally a disease of unregulated cell growth and circumvented cell death; therefore biomarkers focused on these two cellular processes are valuable in the various stages of drug development for many cancer types.  Few commonly used biomarkers offer the sensitivity and specificity needed to efficiently take drugs through all stages of development and clinical uses.  Thymidine Kinase 1 (TK1) is an old biomarker with a new use in solid tumor studies, while Keratin 18 is a useful biomarker for assessing and distinguishing between necrotic vs apoptotic cell death.  

    This talk aims to introduce these two biomarkers as superior options to use over other biomarkers and present data to support their value in developing drugs to target solid tumors.


    Show Resources
    You May Also Like
    OCT 02, 2019 11:00 AM PDT
    OCT 02, 2019 11:00 AM PDT
    DATE: October 2, 2019TIME: 11:00am PDT, 2:00pm EDT Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS Achieve configuration of molecular workf...
    JAN 23, 2020 9:00 AM PST
    C.E. CREDITS
    JAN 23, 2020 9:00 AM PST
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    SEP 05, 2019 4:00 PM CEST
    C.E. CREDITS
    SEP 05, 2019 4:00 PM CEST
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    NOV 18, 2019 7:00 AM PST
    C.E. CREDITS
    NOV 18, 2019 7:00 AM PST
    DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
    FEB 26, 2020 9:00 AM PST
    C.E. CREDITS
    FEB 26, 2020 9:00 AM PST
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    MAR 03, 2020 9:00 AM JST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    MAR 03, 2020 9:00 AM JST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: March 3, 2020 TIME: 9:00am JST A major limitation in the ex vivo expansion of harvested human hematopoietic stem-progenitor cells (HSPCs) is the rapid differentiation of HSPCs at the e...
    Loading Comments...
    Show Resources