MAR 16, 2017 6:00 AM PDT

Working Memory: Neurophysiological Basis, Development, and Plasticity

Presented at: Neuroscience 2017
Speaker

Abstract

Working memory ability matures late in life, in adolescence or early adulthood, and may be enhanced even in adulthood through cognitive training. The mechanisms through which working memory is mediated, and how it is modified so as to mediate such cognitive changes have been a matter of debate in recent years. To address this question, my laboratory has performed a series of experiments recording neuronal activity in adolescence and adulthood, as well as before and after training on working memory tasks. Neural activity comparisons between adolescent and adulthood revealed unchanged representation of visual stimuli, increased activation during working memory, but decreased representation of distracting stimuli. After task training, more prefrontal neurons were activated by the stimuli, and increased activity was present during working memory maintenance. These results reveal the nature of changes in neural activity that underlie cognitive enhancement in development and as a result of task training.


Show Resources
You May Also Like
JUN 28, 2022 7:00 AM PDT
JUN 28, 2022 7:00 AM PDT
Date: June 28, 2022 Time: 3:00pm (BST), 4:00pm (CET), 9:00am (CST), 7am (PST) Light-sheet microscopy is an extremely versatile imaging technique with a vast range of implementations that are...
AUG 24, 2022 7:00 AM PDT
AUG 24, 2022 7:00 AM PDT
Date: August 24, 2022 Time: 7:00am (PDT), 10:00pm (EDT), 4:00pm (CEST) Light field microscopy was first introduced in 2006, and allows users to capture the 4D light field within the microsco...
JUN 21, 2022 6:00 AM PDT
JUN 21, 2022 6:00 AM PDT
Date: June 21, 2022 Time: 6:00am (PDT), 9:00am (EDT), 3:00pm (CEST) The global understanding and practice of medicine is currently undergoing a revolutionary change. This shift to precision...
APR 26, 2022 7:00 AM PDT
C.E. CREDITS
APR 26, 2022 7:00 AM PDT
Date: April 19, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) High-content (HC) phenotypic profiling approaches are a powerful tool to study the effect of biological, genetic, and ch...
OCT 11, 2022 8:00 AM PDT
C.E. CREDITS
OCT 11, 2022 8:00 AM PDT
Date: October 11, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Multiomic profiling of cell populations at single-cell resolution is revolutionizing scientists’ understanding o...
MAR 02, 2022 9:00 AM PST
C.E. CREDITS
MAR 02, 2022 9:00 AM PST
Date: March 02, 2022 Time: 9:00am (PST), 12:00pm (EST) Single cell RNA-seq is known to only capture a small fraction of the transcriptome of each cell. Often, this is due to inherent limitat...
MAR 16, 2017 6:00 AM PDT

Working Memory: Neurophysiological Basis, Development, and Plasticity

Presented at: Neuroscience 2017


Show Resources
Loading Comments...
Show Resources