DEC 05, 2018 9:00 AM PST

Making the most of your mouse model with bead-based multiplexing

Sponsored by: Luminex
Speaker

Abstract

DATE: December 5, 2018
TIME:  9:00AM PST

The mouse is a critical, increasingly used model system in biomedical research and preclinical drug discovery. While technological advances enable complex genetic manipulations that result in increased translational relevance, one distinct limitation remains - sample volume.

In addition, preclinical research increasingly demands measurement of multiple biomarkers (cytokines, chemokines, and growth factors) to characterize signaling pathways accurately or to analyze the effects of an intervention. Unfortunately, researches are often forced to design experiments around sample limitations.

The Bio-Plex® Multiplex System, powered by Luminex xMAP® Technology enables the quantification of more than 500 different protein or peptide targets simultaneously from a single sample volume. More specifically, the Bio-Plex Pro™ Mouse Cytokine, Chemokine, and Growth Factor Magnetic Bead-Based Assays detect and measure levels of 46 analytes in diverse matrices such as serum, plasma, and tissue culture supernatants.

This presentation will provide an overview of multiplexing technology for research use with mouse samples, and highlight the associated benefits to the drug discovery workflow.

 

Learning Objectives:

  • What xMAP Technology is and how it is used
  • Mouse models in research
  • Common challenges and solutions with multiplexing technology
  • Features of xMAP-based multiplexing vs. other options for quantitation:

          - Reduced sample volume usage

          - Enhanced dynamic range and quantitation in contrast to ELISA

          - Global profiling and pathway analysis

          - Increased throughput capabilities coupled with reduced cost and time inputs

          - Superior data accuracy


Show Resources
You May Also Like
SEP 14, 2021 7:00 AM PDT
C.E. CREDITS
SEP 14, 2021 7:00 AM PDT
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
SEP 17, 2021 12:00 PM CST
C.E. CREDITS
SEP 17, 2021 12:00 PM CST
Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
JUL 15, 2021 9:00 AM PDT
JUL 15, 2021 9:00 AM PDT
Date: July 15, 2021 Time: 9:00am (PDT), 12:00pm (EDT) The Pisces workflow robust, easy-to-use, end-to-end multi-omics solution for highly multiplexed targeted Spatial RNA analysis. VeranomeB...
JUN 08, 2021 9:00 AM PDT
JUN 08, 2021 9:00 AM PDT
Date: June 8, 2021 Time: 9:00am PDT Reducing the spread of highly infectious and deadly diseases within the population, vaccine development is crucial in saving millions of lives each year....
DEC 09, 2021 11:00 AM PST
C.E. CREDITS
DEC 09, 2021 11:00 AM PST
Date: December 09, 2021 Time: 11:00am (PDT), 2:00pm (EDT) The burden of antimicrobial resistance (AMR) has been acknowledged worldwide by leading health institutes. Besides the need for new...
SEP 09, 2021 8:00 AM PDT
C.E. CREDITS
SEP 09, 2021 8:00 AM PDT
Date: September 09, 2021 Time: 8:00am (PDT), 11:00am (EDT) Human pluripotent stem cells (PSCs) hold great potentials in regenerative therapies. In this webinar, Chao will first present the c...
DEC 05, 2018 9:00 AM PST

Making the most of your mouse model with bead-based multiplexing

Sponsored by: Luminex


Show Resources
Loading Comments...
Show Resources