MAY 14, 2015 06:00 AM PDT

Next-generation sequencing for BRCA1 and BRCA2 mutation testing

Speakers
  • Director, Head of Biological research content, Qiagen, Inc.
    Biography
      Dr. Devgan is the head of the Biological Research Content, QIAGEN. He received his Ph.D. in molecular biology and conducted post-doctoral research at Harvard Medical School before moving to the biotechnology industry. He received his MBA from the University of Wurzburg in Germany and has spent many years as a scientist in developing new technologies and products clinical and translational research.

    Abstract:

    Cancer is complex, but recent findings are yielding a greater understanding of the disease. The tumor suppressor genes BRCA1 and BRCA2 are implicated in breast, ovarian, prostate, and other cancers. Studying mutations along the entire length of these genes will bring us closer to winning the fight against cancer, so every base of BRCA1 and BRCA2 is important to your cancer research. QIAGEN recently launched the GeneRead DNAseq BRCA1/2 Targeted Panel covering 100% of the coding region and intron-exon junctions, enabling you to analyze every base of the BRCA1 and BRCA2 genes. This presentation will cover the development, experimental verification, NGS workflow, and data interpretation associated with the BRCA1/2 targeted DNA sequencing panel. Learning objectives: 1. Critical success factors for BRCA1 and BRCA2 testing 2. Challenges and solutions for BRCA1 and BRCA2 testing in FFPE samples 3. Application of targeted sequencing strategy for BRCA genes in blood and FFPE samples


    Show Resources
    You May Also Like
    MAY 03, 2018 11:00 AM PDT
    MAY 03, 2018 11:00 AM PDT
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    MAY 22, 2018 08:00 AM PDT
    C.E. CREDITS
    MAY 22, 2018 08:00 AM PDT
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    MAY 24, 2018 09:30 AM PDT
    C.E. CREDITS
    MAY 24, 2018 09:30 AM PDT
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    APR 27, 2018 10:00 AM PDT
    C.E. CREDITS
    APR 27, 2018 10:00 AM PDT
    DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
    AUG 15, 2018 08:00 AM PDT
    C.E. CREDITS
    AUG 15, 2018 08:00 AM PDT
    DATE: August 15, 2018TIME: 08:00AM PDT, 11:00AM EDTThe failure of current chemotherapeutic strategies in the fight against cancer can be largely attributed to the occurrence of drug res...
    MAY 02, 2018 08:00 AM PDT
    C.E. CREDITS
    MAY 02, 2018 08:00 AM PDT
    Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimized to prevent non-specific background effects, artifacts, o...
    Loading Comments...