NOV 06, 2017 8:00 AM PST

WEBINAR: Rapid PGS workflow using next-generation sequencing

Speakers
  • Fertas Laboratory Scientific Director; Centre for Medically Assisted Procreation (CPMA) Senior clinical embryologist ESHRE
    Biography
      Dr. Fabien Murisier graduated as a biologist at the University of Lausanne in 2002, became a Doctor of Science (PhD) in 2006 and then joined the Human Genetics Unit of the MRC in Edinburgh. His research focused on the genetics of embryonic development. Dr. Murisier was honored to receive the award from the Faculty of Biology and Medicine of the University of Lausanne in 2007.

      In 2007, he joined the Laboratory of Reproductive Biology of the CPMA and he acquired the ESHRE certification of clinical embryologist in 2010. Since 2013, he is responsible for the in vitro fertilization laboratory of Fribourg, Switzerland. Dr. Murisier is scientific director of the Fertas laboratory since 2011
    • Director, Bioarray
      Biography
        Luis is technical manager and co-founder of Bioarray. He developed his scientific career in different fields related to molecular biology, from gene sequencing to drug discovery, but always with a strong interest in bioinformatics. He obtained his PhD degree in proteomics. During his postdoc, he changed the course of his research to developing biosensors, working in a project to detect biomarkers in the culture media of human embryo related to aneuploidy. At the same time, he funded Bioarray with Andrés Antón. From this moment, Luis has been working passionately in microarrays and next generation sequencing applied to genetic diagnosis.

      Abstract:

      DATE: November 6, 2017
      TIME: 08:00am PST, 11:00am EST, 5:00pm CET

       

      Set-up of a PGS platform: the Swiss experience

      Dr. Murisier’s lab investigated the different technical solutions available and implemented the Ion ReproSeq PGS Kit for S5. The verification and implementation of this platform by a multi-disciplinary team composed of embryologists, geneticists and molecular biologists, will be presented with an emphasize on mosaicism and segmental deletions/duplications. Dr. Murisier’s perspectives on ART applications will also be discussed.

      Combined PGD and PGS on single embryo biopsy

      Dr. Luis Alcaraz will demonstrate how to detect simultaneously aneuploidies and monogenic variants of interest, using Ion ReproSeq PGS Kits. The workflow is in less than 16 hours, from amplification to reporting, making the process ready for the complete range of ART procedures.


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