Webinars

JUN 29, 2023 7:55 PM PDT

RNA Interference - From Single Gene Studies to Whole Genome Screens

Sponsored by: MilliporeSigma

9 +10pts

Speaker

Abstract

RNA interference (RNAi) offers a fast and easy system to study gene functions. However, the traditionally used small interfering RNAs (siRNAs) can exhibit pronounced and problematic off-target effects.

RNA interference (RNAi) is a widely applied method, offering a fast and easy system to study gene functions. In this talk, we will take a look at the technology of endoribonuclease-prepared siRNAs (esiRNA) to overcome the limitations of RNAi and show the advantages over standard siRNAs.

We demonstrate how this technology is used in various research fields such as stem cell biology, cancer, and cell biology, and evolutionary and developmental biology. Demonstrated uses include both in vitro and in vivo applications, from single-gene studies to genome-wide screens.

This webinar is for anyone interested in RNAi, whether you are an academic researcher or a researcher in R&D.

Learning Objectives

An alternative type of siRNA—endoribonuclease-prepared siRNAs (esiRNAs).
How esiRNAs overcome limitations of traditional siRNAs in RNAi.
Real-world examples of esiRNA use, including stem cell biology, cancer, and developmental biology applied in vitro and in vivo, from single-gene studies to genome-wide screens.

Webinars will be available for unlimited on-demand viewing after live event.

RNA Interference - From Single Gene Studies to Whole Genome Screens

Julia Krüger, PhD