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    Follow

    Gene Silencing

    Gene Silencing: describes the epigenetic regulation of a gene, at the level of transcription or translation, to prevent gene expression. Mechanisms include DNA methylation, histone modification and RNAi. Methods to silence genes are exploited by researchers to study gene function, and for the development of therapeutics for diseases including cancer, infectious diseases and neurodegenerative disorders.

    What's Popular in Gene Silencing

    Trending News

    • APR 15, 2025
      Genetics & Genomics
      Novel Parkinson's Linked Genes Revealed by CRISPR
      Novel Parkinson's Linked Genes Revealed by CRISPR
      Parkinson's disease is the second most common neurodegenerative disease in the world...
      Written By: Carmen Leitch
      3
      FEB 20, 2024
      Genetics & Genomics
      Ancient Viruses Boosted Vertebrate Brain Evolution
      Ancient Viruses Boosted Vertebrate Brain Evolution
      In DNA, retrotransposons can move around and insert themselves into other parts of genomes with a kind of copy and paste ...
      Written By: Carmen Leitch
      6 1
      FEB 02, 2024
      Genetics & Genomics
      Why do Women Get More Autoimmune Disease? Scientists Find an Answer
      Why do Women Get More Autoimmune Disease? Scientists Find an Answer
      Millions of people have autoimmune diseases, such as multiple sclerosis or rheumatoid arthritis  but it's estim ...
      Written By: Carmen Leitch
      6 1
      JAN 18, 2024
      Immunology
      Novel Work Informs How a Cell Pathway Activates Innate Immunity
      Novel Work Informs How a Cell Pathway Activates Innate Immunity
      Different pathways within the cell are activated or silenced dependent on the external signals acting on a cell. One suc ...
      Written By: Brian G. Morreale
      5
      JAN 17, 2024
      Genetics & Genomics
      Lassoing Gene Expression with Genomic Loops
      Lassoing Gene Expression with Genomic Loops
      DNA molecules are very lengthy, and most cells in the body have to fit the entire genome into the nucleus. To do so, the ...
      Written By: Carmen Leitch
      5
    APR 15, 2025
    Genetics & Genomics
    Novel Parkinson's Linked Genes Revealed by CRISPR
    Novel Parkinson's Linked Genes Revealed by CRISPR
    Parkinson's disease is the second most common neurodegenerative disease in the world...
    Written By: Carmen Leitch
    3
    FEB 20, 2024
    Genetics & Genomics
    Ancient Viruses Boosted Vertebrate Brain Evolution
    Ancient Viruses Boosted Vertebrate Brain Evolution
    In DNA, retrotransposons can move around and insert themselves into other parts of genomes with a kind of copy and paste ...
    Written By: Carmen Leitch
    6 1
    FEB 02, 2024
    Genetics & Genomics
    Why do Women Get More Autoimmune Disease? Scientists Find an Answer
    Why do Women Get More Autoimmune Disease? Scientists Find an Answer
    Millions of people have autoimmune diseases, such as multiple sclerosis or rheumatoid arthritis  but it's estim ...
    Written By: Carmen Leitch
    6 1
     
     
    JAN 18, 2024
    Immunology
    Novel Work Informs How a Cell Pathway Activates Innate Immunity
    Novel Work Informs How a Cell Pathway Activates Innate Immunity
    Different pathways within the cell are activated or silenced dependent on the external signals acting on a cell. One suc ...
    Written By: Brian G. Morreale
    5
    JAN 17, 2024
    Genetics & Genomics
    Lassoing Gene Expression with Genomic Loops
    Lassoing Gene Expression with Genomic Loops
    DNA molecules are very lengthy, and most cells in the body have to fit the entire genome into the nucleus. To do so, the ...
    Written By: Carmen Leitch
    5
    SEP 26, 2023
    Genetics & Genomics
    New Insights Into How to Treat a Common Form of Muscular Dystrophy
    New Insights Into How to Treat a Common Form of Muscular Dystrophy
    Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common forms of muscular dystrophy that impacts almost ...
    Written By: Carmen Leitch
    5
    SEP 08, 2023
    Drug Discovery & Development
    Double dose of this cancer treatment rejuvenates immune cells in Head and Neck Cancer
    Double dose of this cancer treatment rejuvenates immune cells in Head and Neck Cancer
    Groundbreaking clinical trial that unveils the power of neoadjuvant anti-PD-1 therapy in head and neck squamous cell car ...
    Written By: Amielle Moreno
    5
    APR 27, 2023
    Cell & Molecular Biology
    Researchers Slow Aging in Cells
    Researchers Slow Aging in Cells
    Scientists are still determining whether humans will reach a maximum possible age or if we can extend lifespan indefinit ...
    Written By: Carmen Leitch
    3
    JAN 23, 2023
    Neuroscience
    Tau tangles unravel when these three genes are silenced
    Tau tangles unravel when these three genes are silenced
    By controling the activity of an enzyme called CHIP, three proteins regulate tau. Now the genes for these three trouble ...
    Written By: Amielle Moreno
    1
    See More
    Gene Silencing
    Trending News
    See All

    Webinars

    • JUN 29, 2023 | 7:55 PM
      RNA Interference - From Single Gene Studies to Whole Genome Screens
      RNA Interference - From Single Gene Studies to Whole Genome Screens
      RNA interference (RNAi) offers a fast and easy system to study gene functions. However, the traditionally used small interfering RNAs (siRNAs) can exhibit pronounced and problematic off-targ...
      Speaker: Julia Krüger, PhD
      Sponsored By: MilliporeSigma
      9
      NOV 03, 2021 | 10:00 AM
      Streamline your path from immunodiagnostic development to commercialization
      Streamline your path from immunodiagnostic development to commercialization
      Date: November 3, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Developing and commercializing immunodiagnostic assays are challenging and time-consuming. Selecting the best combination of tools an...
      Speaker: Anthony Chiulli
      Sponsored By: Thermo Fisher Scientific
      3
      AUG 25, 2021 | 12:00 AM
      The Long Hangover: Adolescent Intermittent Ethanol's Effects on Hippocampal Neuroimmune and Cell Death Markers, Reversal by Donepezil
      The Long Hangover: Adolescent Intermittent Ethanol's Effects on...
      Adolescence is a critical period for the developing brain, and binge drinking during this neuromaturation can result in enduring abnormal brain function and behavior. Repeated adolescent bin...
      Speaker: Kati Healey, MA, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      1
      MAR 31, 2021 | 9:00 AM
      Gene inactivation by CRISPRi: Modulate gene expression with PAM-anchored targeting
      Gene inactivation by CRISPRi: Modulate gene expression with PAM-anchored...
      Date: March 31, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Knockdown studies are prevalent and powerful ways to illustrate gene function. CRISPRi delivers a new mechanism for gene knockdown, PAM...
      Speaker: Steve Smith, PhD, MBA
      Sponsored By: Horizon Discovery
      13 2
      NOV 19, 2020 | 9:00 AM
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Highly specific multiplexed RNA imaging in tissues with split-FISH
      Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
      Speaker: Kok Hao Chen , Alan Mullan, PhD
      Sponsored By: Andor
      6 2
    JUN 29, 2023 | 7:55 PM
    RNA Interference - From Single Gene Studies to Whole Genome Screens
    RNA Interference - From Single Gene Studies to Whole Genome Screens
    RNA interference (RNAi) offers a fast and easy system to study gene functions. However, the traditionally used small interfering RNAs (siRNAs) can exhibit pronounced and problematic off-targ...
    Speaker: Julia Krüger, PhD
    Sponsored By: MilliporeSigma
    9
    NOV 03, 2021 | 10:00 AM
    Streamline your path from immunodiagnostic development to commercialization
    Streamline your path from immunodiagnostic development to commercialization
    Date: November 3, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Developing and commercializing immunodiagnostic assays are challenging and time-consuming. Selecting the best combination of tools an...
    Speaker: Anthony Chiulli
    Sponsored By: Thermo Fisher Scientific
    3
     
     
    AUG 25, 2021 | 12:00 AM
    The Long Hangover: Adolescent Intermittent Ethanol's Effects on Hippocampal Neuroimmune and Cell Death Markers, Reversal by Donepezil
    The Long Hangover: Adolescent Intermittent Ethanol's Effects on...
    Adolescence is a critical period for the developing brain, and binge drinking during this neuromaturation can result in enduring abnormal brain function and behavior. Repeated adolescent bin...
    Speaker: Kati Healey, MA, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    1
    MAR 31, 2021 | 9:00 AM
    Gene inactivation by CRISPRi: Modulate gene expression with PAM-anchored targeting
    Gene inactivation by CRISPRi: Modulate gene expression with PAM-anchored...
    Date: March 31, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Knockdown studies are prevalent and powerful ways to illustrate gene function. CRISPRi delivers a new mechanism for gene knockdown, PAM...
    Speaker: Steve Smith, PhD, MBA
    Sponsored By: Horizon Discovery
    13 2
    NOV 19, 2020 | 9:00 AM
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Highly specific multiplexed RNA imaging in tissues with split-FISH
    Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
    Speaker: Kok Hao Chen , Alan Mullan, PhD
    Sponsored By: Andor
    6 2
    SEP 30, 2020 | 10:30 AM
    Straightforward CRISPR knockout: Leveraging predesigned synthetic sgRNAs for highly functional and specific gene knockout
    Straightforward CRISPR knockout: Leveraging predesigned synthetic...
    CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
    Speaker: James Goldmeyer, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: Horizon Discovery
    3 1
    SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
    SEP 08, 2020 | 9:00 AM
    Keynote Presentation: A Universal Influenza Virus Vaccine
    Keynote Presentation: A Universal Influenza Virus Vaccine
    Seasonal and pandemic influenza virus infections can cause significant disease worldwide. Current vaccines only provide limited, short-lived protection, and antigenic drift/shift in the hema...
    Speaker: Peter Palese, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    3
    JUL 22, 2020 | 10:00 AM
    Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
    Molecular Diagnostic Solutions in a Pandemic: Planning for the...
    DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
    Speaker: Heba Mostafa, MD, PhD, D(ABMM)
    Sponsored By: GenMark Dx
    27 13
    See More
    Gene Silencing
    Webinars
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    Virtual Events

    • SEP 29, 2020  | 6:00 AM PDT
      Applied Biosystems Genetic Analysis Virtual Conference
      Applied Biosystems Genetic Analysis Virtual Conference
      Due to the fact that many large events and scientific conferences have been cancelled, we want to provide you with an outlet to present your research and learn from others in our community....
      28
      MAY 08, 2019  | 6:00 AM PDT
      C.E. CREDITS
      Genetics and Genomics Virtual Event Series 2019
      Genetics and Genomics Virtual Event Series 2019
      Labroots and the Genetics and Genomics planning committee are excited to announce they will be hosting the 7th Annual Event in the Genetics and Genomics Virtual Event Series on May 8-9, 2019....
      54 3
      NOV 14, 2018
      6th annual 24 Hours of Stem Cells™ virtual event
      6th annual 24 Hours of Stem Cells™ virtual event
      Register for free to attend the 6th annual Gibco™ 24 Hours of Stem Cells™ virtual event, the largest global virtual stem cell event taking place around the world on November 15, 2...
      61 4
      NOV 14, 2018  | 6:00 AM PST
      Clinical Diagnostics & Research Virtual Event Series 2018
      Clinical Diagnostics & Research Virtual Event Series 2018
      Labroots invites you to the 9th Annual Event in the Clinical Diagnostics & Research Virtual Event Series!...
      29
      OCT 10, 2018  | 6:00 AM PDT
      Cancer Research & Oncology Week Virtual Event Series 2018
      Cancer Research & Oncology Week Virtual Event Series 2018
      The 6th Annual Event in the Cancer Research & Oncology Week Virtual Event Series will take place October 2018....
      31 3
    SEP 29, 2020  | 6:00 AM PDT
    Applied Biosystems Genetic Analysis Virtual Conference
    Applied Biosystems Genetic Analysis Virtual Conference
    Due to the fact that many large events and scientific conferences have been cancelled, we want to provide you with an outlet to present your research and learn from others in our community....
    28
     
     
    MAY 08, 2019  | 6:00 AM PDT
    C.E. CREDITS
    Genetics and Genomics Virtual Event Series 2019
    Genetics and Genomics Virtual Event Series 2019
    Labroots and the Genetics and Genomics planning committee are excited to announce they will be hosting the 7th Annual Event in the Genetics and Genomics Virtual Event Series on May 8-9, 2019....
    54 3
    NOV 14, 2018
    6th annual 24 Hours of Stem Cells™ virtual event
    6th annual 24 Hours of Stem Cells™ virtual event
    Register for free to attend the 6th annual Gibco™ 24 Hours of Stem Cells™ virtual event, the largest global virtual stem cell event taking place around the world on November 15, 2...
    61 4
    NOV 14, 2018  | 6:00 AM PST
    Clinical Diagnostics & Research Virtual Event Series 2018
    Clinical Diagnostics & Research Virtual Event Series 2018
    Labroots invites you to the 9th Annual Event in the Clinical Diagnostics & Research Virtual Event Series!...
    29
    OCT 10, 2018  | 6:00 AM PDT
    Cancer Research & Oncology Week Virtual Event Series 2018
    Cancer Research & Oncology Week Virtual Event Series 2018
    The 6th Annual Event in the Cancer Research & Oncology Week Virtual Event Series will take place October 2018....
    31 3
    MAR 22, 2016  | 7:00 AM PDT
    C.E. CREDITS
    GENETICS IN YOUR CLINIC: WHAT YOU CAN AND SHOULD DO NOW
    GENETICS IN YOUR CLINIC: WHAT YOU CAN AND SHOULD DO NOW
    Applying the Latest Genetics Findings to Your PracticeAn ASHG Global Virtual Meeting, March 22, 2016 5am Pacific, 8am Eastern, 1pm GMTPrimary audience: Primary care clinicia...
    28 11
    MAY 13, 2015  | 5:00 AM PDT
    Genetics and Genomics Virtual Event Series 2015
    Genetics and Genomics Virtual Event Series 2015
    Welcome to the 3rd Annual Event in the Genetics and Genomics Virtual Event Series! The event is now available on-demand and you can attend sessions including keynotes sessions...
    98 83
    MAR 19, 2014  | 6:00 AM PDT
    Neuroscience Virtual Event Series 2014
    Neuroscience Virtual Event Series 2014
    Labroots is excited to present the 1st annual event in the Neuroscience Virtual Event Series!...
    1180
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