Role of Chromosomal Microarray in the Era of Genome Sequencing

 

Advancements in technologies have revolutionized the genetic landscape. Chromosomal microarray analysis (CMA) becomes a proven method and is implemented to detect gains and losses of DNA and absence of heterozygosity across the genome. Next-generation sequencing technologies have brought opportunities and challenges to genetic testing, its prenatal application is an emerging field. We describe our experience using FetalChip, a CMA for prenatal research developed in our laboratory and describe the role of CMA in the era of genome sequencing.

 

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