MAR 22, 2018 08:00 AM PDT
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Simple and effective tools for antibody-drug conjugate screening and characterization
Presented at the Protein and Cell Analysis Education Series Virtual Event
3 9 1958

  • Staff Scientist, Thermo Fisher Scientific
      Chris Langsdorf received his degree in Biochemistry from Oregon State University. He frequently travels internationally to present scientific lectures and seminars to a wide range of audiences. As a staff scientist at Thermo Fisher Scientific, Chris has developed novel fluorescent compounds for use in characterizing disease at a cellular level. He has developed tools for the study of stem cells, apoptosis and cytotoxicity, endocytosis, innate and adaptive immunity, cell proliferation, and the cell cycle.


    Antibody drug conjugates (ADCs) represent a novel method to deliver a drug to diseased cell using the specific antigen-binding capability and internalization process. Antibodies that do not internalize efficiently will have sub-optimal therapeutic results.

    This webinar will introduce reactive chemistries, bright and versatile fluorophores, and powerful detection platforms. You will learn how these novel technologies can advance your ADC discovery and research.

    Learn how to:

    • Use  pH change to detect and measure internalization
    • Perform defined conjugation with the SiteClick™ Antibody Labeling system
    • Quickly and easily screen candidate antibodies for specific internalization


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