MAR 22, 2018 08:00 AM PDT

Simple and effective tools for antibody-drug conjugate screening and characterization

C.E. CREDITS: P.A.C.E. CE | Florida CE
Speakers
  • Staff Scientist, Thermo Fisher Scientific
    Biography
      Chris Langsdorf received his degree in Biochemistry from Oregon State University. He frequently travels internationally to present scientific lectures and seminars to a wide range of audiences. As a staff scientist at Thermo Fisher Scientific, Chris has developed novel fluorescent compounds for use in characterizing disease at a cellular level. He has developed tools for the study of stem cells, apoptosis and cytotoxicity, endocytosis, innate and adaptive immunity, cell proliferation, and the cell cycle.

    Abstract:

    Antibody drug conjugates (ADCs) represent a novel method to deliver a drug to diseased cell using the specific antigen-binding capability and internalization process. Antibodies that do not internalize efficiently will have sub-optimal therapeutic results.

    This webinar will introduce reactive chemistries, bright and versatile fluorophores, and powerful detection platforms. You will learn how these novel technologies can advance your ADC discovery and research.

    Learn how to:

    • Use  pH change to detect and measure internalization
    • Perform defined conjugation with the SiteClick™ Antibody Labeling system
    • Quickly and easily screen candidate antibodies for specific internalization

     


    Show Resources
    You May Also Like
    MAY 22, 2018 08:00 AM PDT
    C.E. CREDITS
    MAY 22, 2018 08:00 AM PDT
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    MAY 24, 2018 09:30 AM PDT
    C.E. CREDITS
    MAY 24, 2018 09:30 AM PDT
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    AUG 15, 2018 08:00 AM PDT
    C.E. CREDITS
    AUG 15, 2018 08:00 AM PDT
    DATE: August 15, 2018TIME: 08:00AM PDT, 11:00AM EDTThe failure of current chemotherapeutic strategies in the fight against cancer can be largely attributed to the occurrence of drug res...
    MAY 03, 2018 11:00 AM PDT
    MAY 03, 2018 11:00 AM PDT
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    APR 27, 2018 10:00 AM PDT
    C.E. CREDITS
    APR 27, 2018 10:00 AM PDT
    DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
    JUN 29, 2018 09:00 AM PDT
    C.E. CREDITS
    JUN 29, 2018 09:00 AM PDT
    DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
    Loading Comments...