MAR 22, 2018 8:00 AM PDT

Simple and effective tools for antibody-drug conjugate screening and characterization

C.E. Credits: P.A.C.E. CE Florida CE
Speakers
  • Staff Scientist, Thermo Fisher Scientific
    Biography
      As a staff scientist at Thermo Fisher Scientific Chris leads a cross-functional team developing fluorescent probes, labeling technologies, and cell-based assays focused on immunotherapy research. Over the last twelve years he has developed more than seventy novel reagents for characterizing disease on a cellular level in areas such as innate and adaptive immunity, cell growth and proliferation, apoptosis and cytotoxicity, and endocytosis. Chris travels frequently to support collaborative research projects and has given over 300 technical seminars and trainings in over thirty countries as part of a scientific education program.

    Abstract:

    Antibody drug conjugates (ADCs) represent a novel method to deliver a drug to diseased cell using the specific antigen-binding capability and internalization process. Antibodies that do not internalize efficiently will have sub-optimal therapeutic results.

    This webinar will introduce reactive chemistries, bright and versatile fluorophores, and powerful detection platforms. You will learn how these novel technologies can advance your ADC discovery and research.

    Learn how to:

    • Use  pH change to detect and measure internalization
    • Perform defined conjugation with the SiteClick™ Antibody Labeling system
    • Quickly and easily screen candidate antibodies for specific internalization

     


    Show Resources
    You May Also Like
    JAN 23, 2020 9:00 AM PST
    C.E. CREDITS
    JAN 23, 2020 9:00 AM PST
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    AUG 27, 2019 9:00 AM PDT
    C.E. CREDITS
    AUG 27, 2019 9:00 AM PDT
    DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
    SEP 05, 2019 4:00 PM CEST
    C.E. CREDITS
    SEP 05, 2019 4:00 PM CEST
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    OCT 02, 2019 11:00 AM PDT
    OCT 02, 2019 11:00 AM PDT
    DATE: October 2, 2019TIME: 11:00am PDT, 2:00pm EDT Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS Achieve configuration of molecular workf...
    JAN 14, 2020 8:00 AM PST
    C.E. CREDITS
    JAN 14, 2020 8:00 AM PST
    DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
    FEB 19, 2020 11:00 AM PST
    C.E. CREDITS
    FEB 19, 2020 11:00 AM PST
    DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
    Loading Comments...
    Show Resources