APR 15, 2020 9:00 AM PDT

Single-cell multi-omics: DNA methylation and 3D genome

Sponsored by: Zymo Research
Speaker

Abstract
DATE:  April 15, 2020
TIME:  9:00am PT, 12:00pm ET
 
We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC reveals coordinated DNA methylation status between distal genomic segments that are in spatial proximity in the nucleus, and delineates heterogeneity of both the chromatin architecture and DNA methylome in a mixed population. It enables simultaneous characterization of cell-type-specific chromatin organization and epigenome in complex tissues.
 
 
 
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