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Smart Cell Monitoring: Resolving the changing needs of cellular research with continuous live-cell analysis

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Head of Applications, BioAnalytics at Sartorius AG
    Biography
      Del Trezise is a highly experienced researcher and leader in the cell-based assay field, with over 25 years of experience in academic, pharmaceutical and biotech settings. Trained to PhD. level in pharmacology and physiology, his postdoctoral research at the University of Cambridge, UK focussed on cell signalling pathways in primary sensory neurones. He went on to pursue a 15-year career in applied drug discovery across a number of divisions of GlaxoSmithKline including senior positions in Neuroscience, Biological Reagents and Assay Development and Compound Screening. In 2009, he left his Director role to co-found Essen BioScience Ltd, a specialist cell-based assay solution provider, where he is currently European Site Head and R&D leader. He has published >35 original papers, reviews and book chapters mostly in the cell-based assay research field.

    Abstract

    The last decade has seen a significant shift in the way that mammalian cells are used in biomedical science. Researchers are increasingly turning from simple, reductionist recombinant cells to primary cells, stem-cell derived cells and advanced in vitro co-culture and organoid models for greater translation and wider application in their work. However, developing and using these different cell systems presents fresh challenges to the everyday researcher. These relate to workflows for cell handling, genetic manipulation, assay development, phenotypic analysis and clinical use in the case of cell therapy.

    • Changing landscape of cellular research
    • Overview of new requirements to monitor these advanced cell systems
    • How continuous live-cell imaging and analysis are aligned to the new biological models

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