NOV 02, 2016 10:30 AM PDT

Tough Targets. Simple Genotyping. Using HRM as a direct approach in research applications.

Speaker
  • Senior Marketing Specialist, Canon BioMedical
    Biography
      Brian McNally received his doctorate in Cell & Molecular Biology at University of Texas Southwestern Medical Center, where he focused on the transcriptional mechanisms governing polycystic kidney disease, renal cancer and development. His post-doctoral fellowship concentrated on the regulatory relationship between the proteasome and Toll-like receptor signaling at the University of Maryland Medical School in the Department of Immunology and Microbiology. Brian has fifteen years of practical experience at the laboratory bench, and his work has been published in peer-reviewed journals and presented at international conferences. In 2008, he transitioned to industry to commercialize new biomedical products including assays, reagents and software. Brian has been with Canon BioMedical since its inception last year. He is passionate about partnering with life scientists to develop the next wave of biomedical solutions.

    Abstract

    Are there DNA targets in your lab that are difficult to genotype using standard PCR or sequencing?
    Do you ever need to genotype a single sample, and you don’t want to wait to batch samples together?
    Are you testing mitochondrial DNA targets? High-resolution melting (HRM) is a PCR-based solution
    that addresses focused genotyping needs. We have developed a library of common and unique
    targets for identifying single nucleotide polymorphisms (SNPs), small indels, and large deletions.
    Using any HRM-enabled thermocycler you get conclusive results in a variety of research areas,
    including cancer, neuroscience, and pharmacogenetics.

    Canon BioMedical was established last year to develop innovative technologies and solutions that
    empower biomedical research and healthcare communities. Our Novallele™ products aim to support
    researchers with 311 targeted genotyping assays as well as laboratory-verified, fast chemistry
    reagents.

    Join us to discuss how our Novallele assays can answer your difficult genotyping questions.

    Learning objectives:
    1. Learn about HRM technology, a PCR-based method for rapid mutation detection.
    2. Learn the mutation types detected with HRM through specific research application examples.


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