Dr. Salzberg's interest in the human genome project motivated him to develop one of the first computational gene-finding systems for the human genome in the early 1990s. His initial collaborations with TIGR at that time led to the development of a gene-finding program, Glimmer, that has been used in the analysis of thousands of microbial genomes, including Borrelia burgdorferi, Mycobacterium tuberculosis, Vibrio cholerae, Bacillus anthracis, and many others. He was a co-founder of the Influenza Genome Sequencing Project, the first large-scale genomics study of human and avian influenza viruses. His current work focuses on algorithms for genome assembly and alignment, particularly emphasizing next-generation sequencing data. In recent years his group developed the Bowtie, TopHat, Cufflinks, and StringTie software for alignment of next-gen sequences from re-sequencing and RNA-seq experiments. All of his group's software is free and open source.
Dr. Salzberg has authored or co-authored two books and over 200 publications in leading scientific journals. He was the 2013 winner of the Benjamin Franklin Award for Open Access in the Life Sciences, and the 2013 winner of the Robert G. Balles Prize in Critical Thinking for his Forbes science blog. In 2001 and again in 2014 he was listed as a Highly Cited Researcher by Thomson Reuters, a compilation of the 1% most-cited researchers in the world; his H-index is 110. He is a Fellow of the American Association for the Advancement of Science and of the International Society for Computational Biology.
Salzberg Lab: http://salzberg-lab.org/