MAY 15, 2019 12:00 PM EDT

Unraveling the legacy and future of Hepatitis B Diagnosis: Clinical impact of conventional molecular tests and HBV-RNA to monitor hepatic infections

Sponsored by: Abbott Molecular
C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Associate Research Fellow, Volwiler Society, Head Infectious Disease Research, Abbott Diagnostics, and Head of Global Viral Surveillance, Emerging Pathogens and New Virus Discovery
    Biography
      Dr. Gavin Cloherty, Associate Research Fellow Volwiler Society, has worked for Abbott for more than seventeen years of which the twelve have been spent in research roles where he provided scientific leadership in the area of infectious disease and diagnostics. Gavin, through the Abbott Global Viral Surveillance Program, studies HIV and hepatitis strains worldwide to monitor changes in circulating strains and emergence of new strains, to identify and characterize rare HIV strains such as HIV-1 groups N, O and P or screen for native HBsAg mutants that may impact diagnostic assay performance. Gavin also conducts translational research for diagnostic technologies, establishing clinical studies, promoting medical education and working with investigators to identify new applications for existing tests and potential new areas of clinical diagnostics.

      Gavin holds a Ph.D. in Molecular Biology from the National University of Ireland, Galway (2001). Gavin received an AMD Presidents Award in 2009 and was inducted into the Abbott Volwiler Society as an Associate Research Fellow in 2014. He is the author of more than 41 publications and has been an invited speaker at numerous national and international scientific meetings and symposia.

    Abstract

    DATE: May 15, 2019
    TIME: 9:00am PDT, 11:00am CDT, 12:00pm EDT

    Hepatitis B infections remain a significant global healthcare burden resulting in 887,000 deaths in 2015. Clinical laboratories can have a measurable impact in improving liver disease care while maximizing healthcare systems efficiencies through the application of high-quality diagnostic technologies. Abbott Laboratories legacy of innovation in hepatitis diagnostics spans decades and continues with the development of an automated assay for the detection of serum HBV pregenomic RNA (pgRNA). Serum HBV pgRNA has been proposed as a marker of HBV cccDNA activity and may be a useful clinical biomarker in evaluating chronic hepatitis B patient response to current nucleoside analogue therapy and aid in the development of novel therapeutic regimens. pgRNA kinetics in conjunction with other molecular and serologic tests may provide insights which aid in the staging and management of people with chronic HBV.

    Learning Objectives:

    • Understand the impact and healthcare burden of Global Hepatitis B Infections.
    • Discover how efforts in assay development led to pregenomicRNA (pgRNA) as an indicator of Hepatis B activity.
    • Comprehend the potential applications of pgRNA in therapy response monitoring.

     

    LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

     


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