AUG 17, 2016 08:00 AM PDT

A Comparison of the Challenges in the Quantification of Fosetyl-Al Tree Nut Residues with CESI-MS/MS and LC-MS/MS

SPONSORED BY: SCIEX, SCIEX
C.E. CREDITS: P.A.C.E. CE
Speakers
  • Director of Research Chemistry, DFA of California
    Biography
      Dr. Wiley Hall currently serves as the Director of Research Chemistry at the DFA of California where he is in charge of fumigation and chemistry research. He received his PhD in chemistry from the University of Delaware where he researched mass spectrometry and atmospheric chemistry. Previously, he worked for the Battelle Memorial Institute in Aberdeen Maryland, developing methods to detect toxic compounds in the environment. He came to the San Joaquin Valley in 2011 and carried out post-doctoral research on methyl bromide recapture following post- harvest fumigations and new analytical methodology to measure fumigant and pesticide residues in agricultural technologies.

    Abstract:

    The export of tree nuts to the European Union (EU) is subject to a maximum residue limit (MRL) of 1.5 ppm for the fungicide fosetyl-Al. As fosetyl-Al readily hydrolyzes to phosphonic acid, the residue of fosetyl-Al is quantitated as the “sum of fosetyl, phosphonic acid, and their salts”. Unfortunately, phosphonate in tree nut extracts can originate from several sources other than fosetyl-Al, particularly when analyzed according to the EURL-SRM method, and if levels of fosetyl-Al exceed the MRL it impacts the export of tree nuts to the EU from the US (valued at $2.7 billion in 2014). The results from a multi-instrument, inter-laboratory study have recently demonstrated the limitations of the current EU methodology, which include:: poor extraction efficiency in tree nuts, low repeatability and of particular concern, false positive results obtained when high levels of phosphate (regularly found in California tree nuts) are present. In this presentation we will discuss the use of capillary electrophoresis, coupled to tandem mass spectrometry (CESI-MS/MS), an orthogonal technique to LC-MS/MS, which has been found to offer a promising alternative addressing these challenges.

    Learning Objectives:

    • Learn about the challenges the tree nut industry is currently facing for exporting tree nuts into the EU
    • See the results produced from a multi-instrument, inter-laboratory study demonstrating the limitations of current methodology for the analysis of fungicides.
    • Learn about an alternative CESI-MS/MS based methodology for analyzing fungicides which overcomes the limitations and technical challenges present with currently utilized methods.

    Show Resources
    You May Also Like
    SEP 12, 2017 08:00 AM PDT
    SEP 12, 2017 08:00 AM PDT
    DATE: September 12, 2017TIME: 8:00am PT, 11:00am ETEvery year, millions of dollars are wasted on poorly characterized and performing antibodies.  Key researchers in the antibody co...
    MAR 22, 2018 10:30 AM PDT
    C.E. CREDITS
    MAR 22, 2018 10:30 AM PDT
    March 22, 2018 09:00AM PST, 1:30 pm EST Cortisol plays a central role in the diagnosis of adrenal excess/insufficiency and in theassessment of stress adaptation and relate...
    MAY 22, 2018 08:00 AM PDT
    C.E. CREDITS
    MAY 22, 2018 08:00 AM PDT
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    AUG 30, 2018 11:00 AM EDT
    C.E. CREDITS
    AUG 30, 2018 11:00 AM EDT
    DATE: August 30, 2018TIME: 11:00am EDT, 5:00pm CEST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturally, as well...
    AUG 30, 2018 10:00 AM CEST
    C.E. CREDITS
    AUG 30, 2018 10:00 AM CEST
    DATE: August 30, 2018TIME:  10:00am CEST, 4:00pm CST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturall...
    MAY 18, 2017 06:00 AM PDT
    C.E. CREDITS
    MAY 18, 2017 06:00 AM PDT
    DATE: May 18th, 2017TIME: 6:00AM PDT 2:00PM UK 3:00PM CETSafety and authenticity of food are major global issues. With an estimated 150 million allergic consumers worldwide an...
    Loading Comments...