PTH Testing in Chronic Kidney Disease Patients

Sponsored by: DiaSorin, DiaSorin
Speakers
  • Professor of Internal Medicine, Director of the Division of Nephrology, Saint Louis University School of Medicine
    Biography
      Dr. Martin is Director of the Division of Nephrology at Saint Louis University and Professor of Internal Medicine. He has served as Chairman of the General Medicine B Study Section of the National Institutes of Health. Dr. Martin's clinical research interests include parathyroid hormone, Vitamin D metabolism and secondary hyperthyroidism. He has authored 230 publications in professional journals, including The New England Journal of Medicine, Kidney International, and The American Journal of Kidney Diseases and Clinical Journal of the American Society of Nephrology.

    Abstract:

    Parathyroid hormone testing is important to monitor the progress of chronic kidney disease (CKD) patients. This presentation will review the basic biochemistry that regulates the calcium, which will explain the importance of PTH and 1,25 dihydroxyvitamin D. After defining the various stages of CKD, the focus will be on monitoring of patients that have progressed toward end stage renal disease (ESRD). It is critical to monitor these patients’ PTH to follow whether therapy is working. The discussion will then turn to advantages of using 1-84 PTH versus intact levels to monitor CKD patients.

    Learning Objectives

    • Define chronic kidney disease and the various stages. At what point along CKD progression are CKD subjects treated and how do PTH levels impact the attending physicians decision making process.
    • Understand Parathyroid Hormone's role in chronic kidney patients. Review the basic biochemistry and break it down to the point that we can understand what a nephrologist looks at in the progression and management of CKD.
    • Understand the difference between intact and 1-84 PTH tests. Discuss why measuring 1-84 vs iPTH is clinically significant - less misdiagnosis and less over treatment
      • more stability allows for more forgiving sample handling 
      • ex vivo oxidation does not impact the 1-84 where it is misinterpreted as instability by iPTH

    Show Resources
    You May Also Like
    SEP 05, 2019 4:00 PM CEST
    C.E. CREDITS
    SEP 05, 2019 4:00 PM CEST
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    AUG 27, 2019 9:00 AM PDT
    C.E. CREDITS
    AUG 27, 2019 9:00 AM PDT
    DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
    FEB 19, 2020 11:00 AM PST
    C.E. CREDITS
    FEB 19, 2020 11:00 AM PST
    DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
    FEB 26, 2020 9:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    FEB 26, 2020 9:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    JAN 23, 2020 9:00 AM PST
    C.E. CREDITS
    JAN 23, 2020 9:00 AM PST
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    NOV 21, 2019 9:00 AM PST
    C.E. CREDITS
    NOV 21, 2019 9:00 AM PST
    DATE: November 21, 2019TIME: 9:00am PST, 12:00pm EST Multiple Myeloma is a disease of terminally differentiated plasma cells with the massive production of monoclonal immunoglobu...
    Loading Comments...
    Show Resources