OCT 03, 2018 1:30 PM PDT

Whole-Genome Identification of CRISPR Targets

Presented at: CRISPR 2018
Speaker
  • Senior Lecturer, Science and Engineering Faculty, Electrical Engineering, Computer Science, Data Science, Queensland University of Technology
    BIOGRAPHY

Abstract

Gene editing using CRISPR is a very promising technology, and it has already had a significant impact on a number of research fields. However, while CRISPR makes targeted modifications easier to achieve, designing suitable guides is not a trivial task. It is crucial to ensure both the efficiency and the safety of the selected target sites. In this presentation, we discuss how to implement relevant selection criteria into an algorithm for whole-genome detection and evaluation of candidate sites. We report on the impact of specific design rules and on results to date. We also outline outstanding computational challenges.

Learning Objectives:

1. Learn how to improve the efficiency of CRISPR knock-outs
2. Understand how computational tools can accelerate gene editing projects
3. Learn about outstanding challenges in making these tools more practical and more widely applicable


Show Resources
You May Also Like
SEP 14, 2021 7:00 AM PDT
C.E. CREDITS
SEP 14, 2021 7:00 AM PDT
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
MAY 11, 2021 10:00 AM PDT
C.E. CREDITS
MAY 11, 2021 10:00 AM PDT
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
SEP 17, 2021 12:00 PM CST
C.E. CREDITS
SEP 17, 2021 12:00 PM CST
Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
JUN 09, 2021 7:00 AM PDT
C.E. CREDITS
JUN 09, 2021 7:00 AM PDT
Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
DEC 09, 2021 11:00 AM PST
C.E. CREDITS
DEC 09, 2021 11:00 AM PST
Date: December 09, 2021 Time: 11:00am (PDT), 2:00pm (EDT) The burden of antimicrobial resistance (AMR) has been acknowledged worldwide by leading health institutes. Besides the need for new...
OCT 12, 2021 9:00 AM PDT
C.E. CREDITS
OCT 12, 2021 9:00 AM PDT
Date: October 12, 2021 Time: 9:00am (PDT), 12:00pm (EDT) SCIEX’s next-generation Biologics Explorer software is an innovative platform for the comprehensive and deep characterization o...
OCT 03, 2018 1:30 PM PDT

Whole-Genome Identification of CRISPR Targets

Presented at: CRISPR 2018

Specialty

Molecular Biology

Genetics

Biotechnology

Gene Expression

Molecular Genetics

Gene Sequencing

Gene

Research And Development

Dna

Research

Dna Sequencing

Disease

Antibodies

Health

Immunology

Geography

Asia54%

North America31%

Europe15%

Registration Source

Website Visitors100%

Job Title

Student31%

Medical Laboratory Technician15%

Clinical Laboratory Scientist8%

Medical Doctor/Specialist8%

Facility/Department Manager8%

Educator/Faculty8%

Biologist8%

Research Scientist8%

Animal Care Lab Technician8%

Organization

Academic Institution38%

Clinical Laboratory15%

Biotech Company8%

Manufacturer - Other8%

Research Institute8%

Medical Center8%

Government8%

Pharmaceutical Company8%


Show Resources
Loading Comments...
Show Resources