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Laboratories use the same laboratory equipment they invested in for COVID testing to perform PGx testing. With COVID testing reimbursement dropping, many laboratorians are considering implem...
Women experience a variety of unique sexual health issues that are often under appreciated by the general public and even by healthcare providers. Compared to other populations, cisgender wo...
The last 20 years have seen an explosion of genetic information and data. New technological advances have made it faster and less expensive to understand the human genomes but most of those...
Comprehending the mechanism behind human diseases with an established heritable component represents the forefront of personalized medicine. Nevertheless, numerous medically important genes...
The Genomes2People Research Program (G2P), led by Robert Green at Brigham and Women’s Hospital, the Broad Institute, Ariadne Labs, and Harvard Medical School, conducts research to acce...
Tandem repeats are hard to assess but important regions on the human genome. There are around 200 pathogenic and phenotypic tandem repeats, which are often ignored by standard analysis. Furt...
This talk will explore the integration of genomics with electronic health records (EHRs) in biobanks, emphasizing its potential to enhance women's health research. We'll delve into h...
Research and medical genomics require comprehensive and scalable solutions to drive the discovery of novel disease targets, evolutionary drivers, and genetic markers with clinical significan...
Genomics, epigenomics and transcriptomics are often thought of as independent fields, but in our clinical practice we use them combined to increase diagnostic yield both for constitutional a...
RNA is dynamic and essential to biological functions. Metatransrciptome captures gene expression (RNAs) of all active microbes in an environment. We care not just 'who is there', but...
The personalized treatment of each cancer patient with targeted therapies selected based on our understanding of the molecular biology of cancer has been the long-standing goal of precision...
Survival rates for patients with high grade serous carcinoma of the ovary (HGSC) have stagnated for the past fifty years. Despite the presence of tumor mutations and infiltration of immune c...
Antibodies against ribonucleoprotein (RNP) are an important serologic marker for mixed connective tissue disease (MCTD). RNP interacts with Smith (Sm) proteins to form the Sm/RNP complex. An...
Despite the remarkable clinical efficacy of chimeric antigen receptor (CAR) T cells in hematological malignancies, only a subset of patients achieve a durable complete response. Furthermore,...
Nanovials are emerging as an accessible platform for performing single-cell functional screening leveraging standard instrumentation, such as flow cytometers and microfluidic single-cell seq...
Chimeric antigen receptor (CAR) T-cell therapy has been extremely successful in treating relapsed/refractory B-cell malignancies, with six CAR T-cell products now FDA approved. Unfortunately...
Throughout history, various approaches including surgery, radiation therapy, chemotherapy, and targeted therapy have been employed in the fight against cancer. In the 2010s, the emergence of...
Brain cancer research stands to benefit from the perspectives, tools, and methodologies of non-traditional fields, such as mechanical engineering. Here, I will discuss our engineering-based...
Understanding the spatial organization of the immune response within tumors is crucial for developing effective cancer immunotherapies. In this seminar, we delve into the interactions betwee...
Adoptive cell therapy (ACT) is an immunotherapy that employs living immune cells to target and destroy cancer cells. However, the inhibitory tumor microenvironment features several obstacles...
A comprehensive exploration of the latest advancements in the pathology of renal tumors. This one-hour webinar will explore the intricacies of renal tumor pathology, focusing on recent devel...
Has your research results or laboratory processes been bogged down by poor staining quality of histology slides? We all know that proper tissue processing is a key element to downstream stai...
Currently we have a chronic pain and mental health epidemic with excessive prescriptions for ssri benzos and opioids. People are unable to feel and process pain. Chronic stress can lead to c...
Cannabinoid hyperemesis syndrome (CHS) is a constellation of intractable vomiting, abdominal pain and hot bathing behavior that solely occurs in the context of heavy chronic use of THC-predo...
Autism spectrum disorder is a group of neurodevelopmental conditions that impact behavior, communication, social interaction, and learning abilities. There has been great interest in using m...
The cannabis plant contains a complex mixture of dozens of known active ingredients, such as phytocannabinoids, terpenes, and flavonoids. The two most prevalent and famed cannabinoids in can...