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Neoantigens are peptides derived from patient-specific and tumor-specific mutations, which can be recognized by the immune system and mediate tumor recognition that leads to immune destructi...
Join this year's poster presenters in the Poster Hall during the Poster Networking Hour, Wednesday, November 8th, from 10:00 AM –11:00 AM PDT , to chat live about their posters and...
Radiation therapy is an important cornerstone of oncologic therapy but is feared to the point of intimidation by too many patients. Yet by the end of treatment, most patients find the experi...
Over the past 10 years, we have come to a greater understanding of the pathogenesis of men who succumb to prostate cancer. One critical aspect is the role of molecular drivers in patients wi...
Recently, a novel hybrid surface technology (HST) has been developed to mitigate metal analyte interactions in liquid chromatography. We have evaluated the performance of instruments and col...
Upon completion of the human genome project, it was determined that greater than 90% of human diseases are due not solely to a person’s genetics but a combination of genetic factors an...
Background: Healthcare access (HCA) encompasses five important dimensions: Affordability, Availability, Accessibility, Accommodation and Acceptability. Published studies of cancer typically...
The lack of diverse participation in clinical research and trials has been a long-standing national problem that has been brought to the forefront due to COVID 19. In cancer research less th...
MicroRNAs (miRNAs) are small RNAs with an average size of 22 nucleotides that regulate gene expression through various mechanisms. During the last decade, researchers have identified over 26...
Brain organoids are self-assembled three-dimensional cellular aggregates with cell types and tissue architectures that resemble the embryonic human brain. As they recapitulate many key featu...
My laboratory uses tools from pharmacology, genomics, and cell signaling to study two key aspects of cancer biology. First, we seek to understand how oncogenic signals, altered metabolic sta...
Bladder cancer is the 4th most prevalent cancer in men, 11th in women and presents one of the highest rates of post-treatment recurrence (70%) among malignancies. Despite its impact on human...
In this webinar, we present a case study on Lynch syndrome (LS), a hereditary condition characterized by a high risk of colorectal cancer, endometrial cancer, and other neoplasia that typica...
We recently determined that concurrent inhibition of autophagy, using the lysosomal inhibitor chloroquine (CQ), and of ERK, using a small molecule ERK inhibitor (ERKi), synergistically suppr...
Nucleic acid analysis is crucial for the diagnostics of infectious diseases such as COVID-19. CRISPR/Cas technology, beyond its broad application in gene editing, features, in this regard, a...
Genomic profiling in various cancers has become standard of care today. Dr. Chandra will discuss the challenges and opportunities of precision oncology testing in community practice and...
Do you have targets that are difficult to genotype? Are you starting new projects and looking for a fast convenient genotyping solution?Whether screening CRISPR clones, exploring pharmaco...
The advent of CRISPR-Cas (Clustered regularly interspaced short palindromic repeats-CRISPR associated) makes it feasible to target/edit the genome with precision. Most of the CRSIPR-Cas syst...
Cells of the liver and pancreas are highly polarized and well differentiated, contributing to food digestion through the secretion of lipid emulsifying bile, and proteolytic juice into the g...
Learning Objectives: 1. Background introduction to AAV gene therapy 2. Novel methods to build AAV capsid libraries for in vivo screening through rational design and directed evolution 3. Tis...
bacteriovorus is a predatory bacterium that preys on Gram-negative bacteria. B. bacteriovorus invades the prey-cell periplasm – the space between the inner and outer membrane – l...
Immunoassays and mass spectrometric assays are the two major methodologies in contemporary clinical chemistry laboratories. While immunoassays are highly automated and offer a faster turnaro...
In the rapidly expanding landscape of molecular diagnostics, the focus is shifting from top to bottom, with a redirection from post-pandemic respiratory testing to developments in gastrointe...
The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of th...
The vaginal microbiome is a critical component of female health. More than 30% of people with vaginas suffer from imbalances in the microbiome (e.g. bacterial vaginosis, yeast infections, an...
For the past years, my laboratory has been working on microfluidic devices to enable the analysis of single cells. Our technology of choice has been droplet microfluidics that encapsulates s...
Neoantigens are peptides derived from patient-specific and tumor-specific mutations, which can be recognized by the immune system and mediate tumor recognition that leads to immune destructi...
