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In recent past respiratory seasons, the world witnessed a “tripledemic” of Influenza (flu), SARS-CoV-2 (COVID-19), and Respiratory Syncytial Virus (RSV). In this presentation, I...
A study of microbiome structure and function associated with plants roots will be presented. the study showed that the microbiome structure is determined by the plant type, with root microbi...
The Cas9 from Francisella novicida (FnCas9) has unique properties of target identification and engagement in terms of specificity, nature of double strand break as well as length of guide RN...
Social interactions are essential for the survival of social animals. Across species the medial prefrontal cortex (mPFC) has been identified as a hub of social cognition. In mouse models we...
Conventional imaging studies such as ultrasound, computed tomography, and magnetic resonance imaging are increasingly detecting small renal masses, which are interpreted by radiologists as h...
CML is traditionally regarded as a paradigm of precision medicine, under several points of view: 1) it is the first human malignancy whose molecular pathogenesis was unravelled, well before...
Drug discovery programs require a robust panel of models and assays to identify and validate drug targets, support compound optimisation, and run mechanistic studies. Fully human in vitro mo...
Invitrogen ProcartaPlex and QuantiGene Plex assays offer the unique ability of a multi-omics high-throughput approach by utilizing the Luminex platform. Genomic and proteomic workflows can b...
Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells are widely used in the biotechnology industry for production of a wide range of therapeutics, predominantly monoclona...
Successful cancer patient advocacy has many components. Patients and survivors are in the best position to tell their stories and advocate for better care and treatment. However, with few su...
CRISPR has revolutionized the biosciences over the past decade. The RNA-targeting CRISPR effector protein Cas13, discovered in 2016, opened up a myriad of new applications for CRISPR-based t...
In the world of advanced medical research, the convergence of synthetic biology and cellular immunotherapy has inaugurated a new era in field of cancer treatment. Simultaneously, life scienc...
The study of human development and diseases relies on analysis of samples obtained and manipulated ex vivo. It is critical in such studies to know the provenance and confirm that the identit...
Targeted proteomics enables hypothesis-driven research by measuring the expression of protein cohorts related by function or disease in systems biology. Here, I highlight a strategy, termed...
BACKGROUND: Chemotherapy-induced nausea and vomiting (CINV) is a debilitating side effect of cancer treatment, affecting up to 40% of patients. Cannabinoid agonists such as nabilone and &Del...
Prof Pantel will give an introduction and review to the evolution of precision medicine and will then focus on the implementation of Liquid Biopsy in Precision Oncology....
The formation of marine snow is an important part of the biological carbon pump as carbon is exported to depth. These particles are composed of cells, minerals, and other sources of organic...
Reliable expression of recombinant proteins in human, CHO, or insect cells is essential for many aspects of biomedical research and drug development, but is often hampered by low expression...
Many behaviors are learned through trial and error by matching performance to internal goals, yet neural mechanisms of performance evaluation remain poorly understood. We recorded basal gang...
Social animals congregate in groups and communicate with vocalizations. To study the dynamics of natural vocal communication and their neural basis, one must characterize signals used for co...
Diosgenin is a botanical steroidal saponin with anti-inflammatory, antioxidant, anti-thrombotic, anti- apoptotic, anti-depressant, and anti-nociceptive properties. However, it's unknown...
The most common forms of pediatric tumors are acute leukemia (33%), brain tumors (25%), and lymphomas (15%). Diagnosing these tumors utilizes various tests, including those performed by a pa...
Use of Ampliseq™ panels to study SARS-CoV-2and the host response to infection Soren Alexandersen 1,2,3 1 Geelong Centre for Emerging Infectious Diseases, Geelong, VIC 3220, Australia;...
Personalized treatment plans for blood cancers rely on the specialized skills of clinical laboratorians using a variety of analytic methods ranging from microscopic examination to molecular...
Across many cancers, mortality is associated with metastasis and acquired drug resistance, both of which often manifest in recurrent disease. Central to these phenomena is epithelial to mese...
The gastrointestinal (GI) epithelium is the body’s first line of defense to luminal contents such as food, microbiota, pharmaceuticals, and toxins. A small pool of proliferative stem a...
The COVID-19 pandemic has underlined the need for an efficient collaboration between scientists, policy makers and the general public to tackle the crisis. Infectious disease experts play a...
In recent past respiratory seasons, the world witnessed a “tripledemic” of Influenza (flu), SARS-CoV-2 (COVID-19), and Respiratory Syncytial Virus (RSV). In this presentation, I...
