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CRISPR has emerged as a promising alternative to viral-based gene editing by allowing scientists to modify genes with unprecedented ease and flexibility. The discovery and development of a d...
10:00am PT, 12:00pm CT, 1:00pm ET: Welcome 10:15am PT, 12:15pm CT, 1:15pm ET: Digital PCR for minimal residual disease research and cancer research Dr. Christopher E. Mason Professor of Geno...
Molecular diagnostic assay development and design is no simple task, and several factors affect the performance and usability of a test. Diagnostic companies can enhance assay stability and...
Measuring the shear rheology for highly temperature sensitive materials is challenging. Material characterization tools are slow compared to industrial processing. Using numerical simulation...
In the last decade or so, R&D into the human microbiome-based therapeutics and diagnostics has accelerated the widespread availability of next-generation DNA sequencing technologies that...
Spatial analysis of protein or gene expression is vital to understanding the distribution, phenotypes, and interactions between cells within tumor microenvironment (TME). Traditionally, mult...
Antimicrobial resistance (AMR) detection and surveillance is a high priority in healthcare and environmental settings for the safety of both patients and the general public. However, working...
The state of healthcare today and tomorrow can be best described as complex and unpredictable. From chronic diseases to neurodegenerative diseases such as Alzheimer’s, infectious disea...
The FDA submitted its final rule regarding laboratory diagnostic tests (LDTs) on May 6, 2024. While it allows for 4 years for compliance and it is currently being disputed by various associa...
To identify genetic variants in archival human samples, researchers need a powerful NGS platform that can accommodate input DNA and RNA that is often low quality and/or low quantity. This ch...
Extrachromosomal circular DNA (eccDNA) comprises products of genomic recombination that cause somatic changes in gene length and sequence. These circular molecules are derived from canonical...
Tandem repeats are hard to assess but important regions on the human genome. There are around 200 pathogenic and phenotypic tandem repeats, which are often ignored by standard analysis. Furt...
Comprehending the mechanism behind human diseases with an established heritable component represents the forefront of personalized medicine. Nevertheless, numerous medically important genes...
Neoantigen vaccines are a type of personalized cancer vaccine. While clinical trials have shown promising results, it is important to note that neoantigen vaccines are still in the early sta...
One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...
The highly competitive nature of academic environments might seem to suggest that success can only be obtained at the cost of taking good care of oneself. However, sacrificing self‐care can...
Comprehensive Genomic profiling (CGP) is becoming standard of care in oncology. It allows clinicians to maximize clinical information from limited biopsy samples so that patients are matched...
Hematuria (blood in urine) may occur in up to 10% of the general population and results in costly evaluation to ensure it is of no consequence, i.e., no bladder cancer (BCa) is present since...
Given its ability to isolate pathogens, nuclei, and immune cells for downstream applications, cell sorting is an essential tool for immunological studies. Yet, the potential for aerosol form...
Oligonucleotide therapeutics have emerged as a promising novel class of drugs to treat a wide range of diseases. The development of these therapeutics relies on the proper use of chemical bu...
Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
CRISPR has emerged as a promising alternative to viral-based gene editing by allowing scientists to modify genes with unprecedented ease and flexibility. The discovery and development of a d...
