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The next leap in oncology therapeutics demands speed, precision, and rapid molecular innovation — and AI-driven antibody design (AIDD) is beginning to deliver. In this talk, we will un...
Learning Objectives: 1. Summarize the benefits and challenges of current preclinical methods in drug discovery and development. 2. Review new alternative methodologies (NAMs) and microphysio...
Traditionally, imaging workflows required significant manual interaction and time investment from the user. The addition of automation has decreased user time commitment and increased data o...
The importance of reference materials in the food and beverage industry is a critical piece of quality control when it comes to getting trustworthy product into consumers hands every day. In...
Operational barriers like complicated workflows and long turnaround times have hindered broad adoption of next-generation sequencing (NGS) in clinical oncology research. The new Ion Torrent...
Our ability to record large-scale neural and behavioral data has substantially improved in the last decade. However, the inference of quantitative dynamical models for cognition and motor co...
At Biogen Idec, we have implemented a 3 part innovation operating model which includes innovation mentoring, agile experimentation and transition of experiments into pilots. In this presenta...
The ongoing surge of clade 2.3.4.4b H5N1 viruses in avian species has resulted in numerous spillover events into mammalian species including dairy cows and humans, posing a potential pandemi...
Our work focuses on developing an optical brain-machine interface capable of interacting with neural activity in real-time. In this talk, I will describe our progress toward building the com...
I will present how I came to choose the physician-scientist career pathway. I was inspired from an early age by stories about my great-grandfather, an academic surgeon who innovated gastric...
At Biogen Idec, we have implemented a 3 part innovation operating model which includes innovation mentoring, agile experimentation and transition of experiments into pilots. In this presenta...
NGS is still perceived as a complex, hard to implement and validate method that requires highly experienced people. Outsourcing next-generation sequencing (NGS) testing could be an option to...
This talk will touch on several key points: PhD (MD) important grounding in science; how to develop friendships, gather mentors and collaborators; keep up with the literature; look at eviden...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
Researchers are increasingly turning to RNA sequencing for gene expression analysis from challenging samples. These samples often include fine needle biopsies, micro-dissected tumors or high...
There is an expanding list of therapeutically relevant biomarkers for non-small cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition in scaling tradi...
Microphysiological systems (MPS) have proven to be a powerful tool for recreating human tissue- and organ-like functions. However, establishing complex human in vitro ADME models involving c...
Quantitative mass spectrometry-based proteomic experiments are designed to answer increasingly complex questions. For example, we may want to characterize changes in protein abundance in bio...
The Brain Behavior Quantification and Synchronization (BBQS) program is a basic research effort in the NIH BRAIN Initiative to develop new tools and approaches in support of a more comprehen...
Currently laboratory research demands more application versatility and certainty for metabolite identification, targeted compound screening, and the ability to identify true unknown compound...
The recent advancements in RNA therapeutics have brought to light the need for mRNA molecules that possess better stability and functionality in vivo....
CRISPR has emerged as a promising alternative to viral-based gene editing by allowing scientists to modify genes with unprecedented ease and flexibility. The discovery and development of a d...
A central goal in single-cell cancer research is to identify phenotypically distinct cells that have prognostic significance for patients. This need is acute in brain tumor glioblastoma, whe...
Molecular diagnostic assay development and design is no simple task, and several factors affect the performance and usability of a test. Diagnostic companies can enhance assay stability and...