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Oligonucleotide therapeutics have emerged as a promising novel class of drugs to treat a wide range of diseases. The development of these therapeutics relies on the proper use of chemical bu...
This talk will explore the integration of genomics with electronic health records (EHRs) in biobanks, emphasizing its potential to enhance women's health research. We'll delve into h...
The webinar highlights advances in high-throughput gene and protein synthesis platforms that accelerate antibody discovery and optimization. Using accurate HTP Strings DNA fragments improves...
As obligate intracellular pathogens, viruses require host-derived nucleotides, amino acids, and lipids, among others, and the bioavailability of these metabolites can restrict or promote vir...
Genomics, epigenomics and transcriptomics are often thought of as independent fields, but in our clinical practice we use them combined to increase diagnostic yield both for constitutional a...
The difficulties in making an accurate diagnosis, the workload in terms of time and the small number of pathologists represent significant problems in laboratory routine. From this perspecti...
My laboratory at the Garvan Institute operates an ISO 15189 and NATA accredited laboratory for testing of patients using whole genome and whole exome sequencing, as well as gene panel testin...
Laws enforcing the prohibition of cannabis have unjustly harmed people of color for nearly a century. As a result, the regulated cannabis industry has a duty to advocate for legalization tha...
Precision oncology is revolutionizing the diagnostic and therapeutic approach to cancer. In fact, the availability of tumor-specific and tumor-agnostic biomarkers and matched therapies is ra...
The evolution of clinical trial design in oncology reflects the current clinical paradigm of personalized medicine, weighing both histology and molecularly-defined biomarkers as the pillars...
Apolipoprotein E epsilon 4 (APOE4) is the primary genetic risk factor for late-onset Alzheimer's disease (AD). APOE4 carriers, especially females, tend to develop gut dysbiosis earlier t...
Recent outbreaks of Ebola virus (EBOV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have exposed our limited therapeutic options for such diseases and our poor understand...
During this seminar I will present details of my path from Beckman Scholar to MD-PhD, advanced training as a neurologist, then a neurointensivist, and the interleaving of additional research...
Wastewater samples are challenging substrates for nucleic acid extraction and the choice of extraction method determines the success of the downstream analysis. Extraction methods must be ab...
Quantitative genetic analysis plays a critical role in the research and development of novel biotherapeutics. As a sensitive and precise method for quantitating specific nucleic acid targets...
Research and medical genomics require comprehensive and scalable solutions to drive the discovery of novel disease targets, evolutionary drivers, and genetic markers with clinical significan...
Infant motor development is measured clinically using short, subjective, observational scales. While these scales are useful, they have limitations. They provide us with a “snapshot&rd...
Hydrogen deuterium exchange (HDX) mass spectrometry (MS) is a powerful tool for studying the dynamics of higher order structure of protein-based therapeutics. In the here presented case stud...
The panel will be followed by an outstanding series of breakout sessions including, Kentucky River Watershed Watch, Kentucky Waterways Alliance, Kentucky Department of Environmental Protecti...
Vestibular sensation anchors our perception of the environment and is crucial for maintaining balance during locomotion. Vertebrate animals use the evolutionarily conserved vestibular system...
The effects of spaceflight on those beneficial microbes that associate with animal tissues is an emerging area in space biology, however, many questions persist regarding how homeostasis bet...