Follow a comprehensive curation of novel and significant discoveries in the fields of genetics and genomics by watching these webinars. Highlighted areas of interest in the fields of genetics and genomics include epigenetics, molecular genetics, hereditary disease, clinical genetics, population genetics, etc.
Altered enteric microorganisms in concert with host genetics shape inflammatory bowel disease (IBD) phenotypes. However, insight is limited to bacteria and fungi. We found that eukaryotic vi...
From Discovery to Clinic: Comprehensive CRISPR Solutions for Therapeutic Development CRISPR gene editing has revolutionized the field of molecular biology, offering precise, efficient, and v...
In-situ multiomics is revolutionizing research in oncology, immunology and neurobiology. However, speed and throughput are major bottlenecks for these critical studies. Here, we present data...
This talk will provide an overview of our work in the design of self-assembled, functionalised peptide and protein nanoparticles, hydrogels and bio-interfaces for applications in healthcare....
Effective control of the spread of HIV depends on using the right antiretroviral drugs. In 2019, the World Health Organization recommended using the integrase inhibitor, dolutegravir (DTG),...
The gastrointestinal (GI) epithelium is the body’s first line of defense to luminal contents such as food, microbiota, pharmaceuticals, and toxins. A small pool of proliferative stem a...
In this talk, I will introduce two new tools that we developed based on CRISPR-enabled gene regulation in bacteria, and one method based on P1 phagemid-enabled delivery of Cas9 nuclease. Fir...
Our understanding of the genetic basis of disease has been rapidly advancing thanks to major technological advances in genomic sequencing and data analysis. Yet the majority of individuals w...
With the fast progress and deeper understanding of CAR-T cell therapy, finding a better solution other than lentivirus transduction is more requested, to overcome the functional limitation o...
Norovirus is a highly contagious virus and stands as the primary cause of acute gastroenteritis leading to vomiting and diarrhea across all age groups in the United States. Outbreaks of noro...
Women experience a variety of unique sexual health issues that are often under appreciated by the general public and even by healthcare providers. Compared to other populations, cisgender wo...
Coronavirus Disease 2019 (COVID-19) has driven the use of nucleic acid testing technology in clinical testing. There is a growing need for point-of-care testing (POCT)......
CRISPR has revolutionized the biosciences over the past decade. The RNA-targeting CRISPR effector protein Cas13, discovered in 2016, opened up a myriad of new applications for CRISPR-based t...
The last 20 years have seen an explosion of genetic information and data. New technological advances have made it faster and less expensive to understand the human genomes but most of those...
In the past decade, gene editing has been increasingly emphasized as an essential tool for therapy development. This has led to significant scientific advances in understanding disease mecha...
CRISPR has emerged as a promising alternative to viral-based gene editing by allowing scientists to modify genes with unprecedented ease and flexibility. The discovery and development of a d...
The personalized treatment of each cancer patient with targeted therapies selected based on our understanding of the molecular biology of cancer has been the long-standing goal of precision...
Programmable genome integration of large, diverse DNA cargo without DNA repair of exposed DNA double-strand breaks remains an unsolved challenge in genome editing. We present programmable ad...
Human respiratory syncytial virus (hRSV) is a significant cause of lower respiratory tract infections in children under the age of 5, the elderly, and immunocompromised individuals, leading...
Comprehending the mechanism behind human diseases with an established heritable component represents the forefront of personalized medicine. Nevertheless, numerous medically important genes...
Join us to explore recent advancements and applications of isothermal amplification techniques, such as LAMP, RCA, and RPA. We will compare these methods with traditional PCR, discuss their...
Oligonucleotide therapeutics have emerged as a promising novel class of drugs to treat a wide range of diseases. The development of these therapeutics relies on the proper use of chemical bu...
Tandem repeats are hard to assess but important regions on the human genome. There are around 200 pathogenic and phenotypic tandem repeats, which are often ignored by standard analysis. Furt...
Genomics, epigenomics and transcriptomics are often thought of as independent fields, but in our clinical practice we use them combined to increase diagnostic yield both for constitutional a...
Altered enteric microorganisms in concert with host genetics shape inflammatory bowel disease (IBD) phenotypes. However, insight is limited to bacteria and fungi. We found that eukaryotic vi...
