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BOC Sciences

(Gln22,Asn23)-Amyloid _-Protein (1-40) | BOC Sciences

(Gln22,Asn23)-Amyloid _-Protein (1-40) is a transgenic mice expressing vasculotropic Dutch/Iowa (E693Q/D694N) mutant human brain A_ precursor protein (TG-SWDI), which accumulates abundant cerebral microvascular fibrillar amyloid deposition and exhibits strong neuroinflammation. In vitro, double-mutated A_ peptides showed a tendency to increase fibrillation and pathogenicity compared with Dutch and Iowa single mutants.

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BOC Sciences specializes in small molecule synthesis, biosynthesis, purification, and characterization. It provides a wide range of research chemicals and biochemicals, including inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities and metabolites, APIs, natural compounds, ADCs, stem cell molecules and chiral compounds.