Name: "shRNA Adeno-associated Virus Serotype 2, pU6-(PIGW-shRNA-Seq1)"
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"shRNA Adeno-associated Virus Serotype 2, pU6-(PIGW-shRNA-Seq1)" | Creative Biolabs

This product is a PIGW-shRNA encoding AAV, which is based on AAV-2 serotype. The protein encoded by PIGW gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). The expression of PIGW-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.