Name: "Anti-EGP2 (XR143) h(CD28-CD3_) CAR, pMMLV"
Availability: InStock

"Anti-EGP2 (XR143) h(CD28-CD3_) CAR, pMMLV" | Creative Biolabs

Recombinant Moloney murine leukemia virus (MMLV) retroviral vectors serve as efficient viral vector tools for introducing genes permanently into a wide variety of dividing cells, and provide an alternative to modify primary T cells. Creative biolabs has developed retroviral CAR vector pMMLV EGP2 (GA733.2) h(28_), which is constructed for the engineering of T cells to target human EGP2. The T cells are genetically modified through transduction with a retroviral vector expressing scFv of anti-EGP2 antibody linked to a CD28 transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of Cancers such as breast cancer, colorectal cancer, gastric cancer, lung cancer, and prostate cancer.