Companies / Creative Biolabs / "Anti-ERBB2_IL13R_2 (XHM313_IL13 mutein ((E13K)) h(CD28-CD3_) TanCAR, pCDCAR1"
Creative Biolabs

"Anti-ERBB2_IL13R_2 (XHM313_IL13 mutein ((E13K)) h(CD28-CD3_) TanCAR, pCDCAR1" | Creative Biolabs

The vector of anti-ERBB2_IL13R_2 tandem chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human ERBB2 and IL13R_2. The T cells are genetically modified through transduction with a lentiviral vector expressing bivalent scFv of anti-ERBB2_IL13R_2 antibody and linked to CD28 and CD3_ signaling domains. And the vector product was designed for the treatment of ERBB2+/IL13R_2+ cancer.

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ABOUT THE COMPANY

Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.