Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
The anti-MAGE4 chimeric antigen receptor (CAR) THP1 cell line is a stable cell line developed using anti-MAGE4 CAR lentivirus transfection. This transfected CAR lentiviral vector is constructed to express a scfv of anti-MAGE4 antibody (EML567) linked to CD147 signaling domains.The anti-MAGE4 CAR engineered THP1 cells can be used to be differentiated into macrophage cells for in vitro or in vivo phagocytosis studies. This CAR-THP1 cell line product can be used for the researches of NSCLC (MAGE-A3/6), metastatic melanoma (70% MAGE-A1-5).
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.