Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
The Anti-ERBB3 (X11X99) h(ICOSBB_) CAR-Jurkat-NFAT-Luc cell line is a stable cell line derived from anti-ERBB3 CAR lentivirus transduction using Jurkat-NFAT-luciferase cell as effector cell. This transduced CAR lentiviral vector was constructed to express scFv of an anti-ERBB3 antibody linked to the ICOS-41BB-CD3_ signaling domains. The CAR-Jurkat cell line constitutively expressing the firefly luciferase gene under the control of NFAT response elements to facilitate subsequent research. And the recombinant cell product targeted ERBB3 for CAR-T studies in human ErbB3 positive cancers.
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.