mouse monoclonal IgG2a; Syndecan-4 Antibody (5G9) is an IgG2a κ mouse monoclonal Syndecan-4 antibody (also designated SDC4 antibody, SYND4 antibody, Amphiglycan antibody or Ryudocan core protein antibody) that detects the Syndecan-4 protein of mouse, rat and human origin by WB, IP, IF and FCM. Syndecan-4 Antibody (5G9) is available as both the non-conjugated anti-Syndecan-4 antibody form, as well as multiple conjugated forms of anti-Syndecan-4 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Syndecans are type I integral membrane proteoglycans that contain both chondroitin sulfate and heparan sulfate groups. Syndecans are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 (SYND1, also called CD138) is an extracellular matrix receptor which binds to collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 (also designated N-Syndecan) interact with MK (midkine), a growth/differentiation factor invloved in embryogenesis of the central nervous system. Syndecan-2 (also designated fibroglycan) is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 (also designated amphiglycan or ryudocan) functions cooperativley with integrins in the processes of cell spreading, focal adhesion assembly and Actin stress fiber assembly.