mouse monoclonal IgM; Moesin Antibody (E-10) is an IgM κ mouse monoclonal Moesin antibody (also designated MSN antibody) that detects the Moesin protein of mouse, rat and human origin by WB, IP, IF and IHC(P). Moesin Antibody (E-10) is available as both the non-conjugated anti-Moesin antibody form, as well as multiple conjugated forms of anti-Moesin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Ezrin, Moesin and Radixin belong to a family of highly homologous Actin-associated proteins that are localized just beneath the plasma membrane. These proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share more than 70% homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation.