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Santa Cruz Biotechnology

VP5 (6F10) Alexa Fluor® 546 | Santa Cruz Biotechnology

mouse monoclonal IgG1; VP5 Antibody (6F10) is an IgG1 κ mouse monoclonal VP5 antibody (also designated VP5 antibody) that detects the VP5 protein. VP5 Antibody (6F10) is available as both the non-conjugated anti-VP5 antibody form, as well as multiple conjugated forms of anti-VP5 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The viral double-stranded DNA of herpes simplex virus type 1 (HSV-1) is contained inside a large and elaborate icosahedral capsid protein shell and surrounded by a membrane envelope. For HSV-1, the outer shell is composed of four proteins: VP5; a small protein bound to hexons, VP26; and a triplex structure made up of heterotrimers of VP19C and VP23. Assembly of the capsomer occurs in the infected-cell nucleus, and the predominant polypetide component of the capsomer is the protein VP5, which is encoded by the gene UL19. VP5 is the structural subunit of both hexons and pentons, which pack together within the intricate lattice of the icosahedral surface. VP5 hexons are hexamers of VP5, and these hexons associate with the scaffolding protein VP26. Pentons comprise pentomers of VP5 and are localized at the capsid vertices.

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ABOUT THE COMPANY

Santa Cruz Biotechnology is a world leader in the development of products for the biomedical research market. Over the past 30+ years, the Company has focused on the ongoing development of research antibodies, siRNA and CRISPR Gene editing tools, biochemicals, labware and more recently has expanded into animal health care products. Santa Cruz Biotechnology has the highest commitment to quality and customer service.