mouse monoclonal IgG2a; HSP 75 Antibody (TR1) is an IgG2a κ mouse monoclonal HSP 75 antibody that detects HSP 75 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. HSP 75 Antibody (TR1) is available as the non-conjugated anti-HSP 75 antibody form, as well as multiple conjugated forms of anti-HSP 75 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock protein 75 mitochondrial precursor (HSP 75), also called tumor necrosis factor type 1 receptor-associated protein (TRAP1), is a 704 amino acid member of the heat shock protein 90 family. HSP 75 localizes to the mitochondrion and is expressed in a variety of tissues, including skeletal muscle, liver, heart, brain, pancreas, lung and placenta, functioning as a chaperone that expresses an ATPase activity.