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    Animal disease model development

    Animal disease models are non-human animals used to research strategies to detect, prevent, or treat human disease. A variety of animals, including mice, rats, rabbits, and non-human primates are used for animal disease modeling. New animal disease models are developed regularly as knowledge of disease expand and technological improvements enhance current models.

    Webinars

    • SEP 13, 2023 | 9:00 AM
      Gibco Cell Culture Heroes - Guy Kunzmann - Investigating the conditionally essential role of protein UFMylation in proliferating human cells
      Gibco Cell Culture Heroes - Guy Kunzmann - Investigating the conditionally...
      CRISPR-based forward genetic screens can be used to identify essential genes in proliferating human cell lines. Although environmental factors also influence gene essentiality, most CRISPR-b...
      Speaker: Guy Kunzmann, BS.
      Sponsored By: Thermo Fisher Scientific
      13
      JUN 15, 2023 | 10:00 AM
      Expanding the frontiers of gene editing: the role of genotypic confirmation
      Expanding the frontiers of gene editing: the role of genotypic...
      Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      18
      JUN 14, 2023 | 8:00 AM
      Expanding the frontiers of gene editing: the role of genotypic confirmation
      Expanding the frontiers of gene editing: the role of genotypic...
      Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      MAY 09, 2023 | 1:00 PM
      Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating the biology of cell-in-cell structures in the human liver using a range of microscopy modalities
      Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating...
      Date: May 09, 2023 Time: 5:00am (PDT), 8:00pm (EDT), 2:00pm (CEST) Advances in high content imaging (HCI) have improved the use of cell culture to make a large number of comparisons within i...
      Speaker: Scott Davies, PhD, MRes, MSci
      Sponsored By: Thermo Fisher Scientific
      10
      MAR 08, 2023 | 8:00 AM
      Considerations to Limit Off-Target Edits in your Gene Editing Experiments
      Considerations to Limit Off-Target Edits in your Gene Editing...
      Date: March 08, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the geno...
      Speaker: Kevin Pridham
      Sponsored By: Thermo Fisher Scientific
      12
      MAR 08, 2023 | 7:30 AM
      Keynote Presentation: Improving Research Translation in Dementia: Humanized Mouse Models, Cognition and Imaging with Live Q&A
      Keynote Presentation: Improving Research Translation in Dementia:...
      Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
      Speaker: Marco A.M. Prado, Pharm, MSc, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      4
      FEB 22, 2023 | 5:30 AM
      Bridging the Gap - How Human Microphysiological Systems Improve the Translatability of NASH Drug Discovery
      Bridging the Gap - How Human Microphysiological Systems Improve...
      Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
      Speaker: Raul Silva
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      2
      NOV 15, 2022 | 9:00 AM
      Reverse engineering the human heart with pluripotent stem cells
      Reverse engineering the human heart with pluripotent stem cells
      Date: November 15, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Recent advances in stem cell technologies, synthetic development and organoid biology are enabling us to create more a...
      Speaker: Aitor Aguirre, PhD
      Sponsored By: BPS Bioscience
      14
      NOV 08, 2022 | 11:00 AM
      Thinking translational: Things to consider in CAR T cell workflows
      Thinking translational: Things to consider in CAR T cell workflows
      Date: November 08, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CET) Developing safe and effective CAR T cell therapies is a challenging task. That’s why thinking translational earl...
      Speaker: Robert Davies
      Sponsored By: Miltenyi Biotec
      9
      NOV 01, 2022 | 10:00 AM
      Flow cytometric gene mutation assay, made possible by immunomagnetic separation, achieves OECD regulatory status
      Flow cytometric gene mutation assay, made possible by immunomagnetic...
      Date: November 01, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 6:00pm (CET) Our laboratory developed the Pig-a gene mutation assay as a means to simply and reliably evaluate the potential mutage...
      Speaker: Jeffrey Bemis, Ph.D. , Joe Ostrand, Ph.D.
      Sponsored By: Miltenyi Biotec
      11
      OCT 05, 2022 | 11:00 AM
      Understanding Fiber in Laboratory Rodent Diets - Definitions, Measurements, and Adjustments
      Understanding Fiber in Laboratory Rodent Diets - Definitions,...
      Date: October 05, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEST) The effects of fiber in health and disease is an active subject of research in a range of research areas. Historically...
      Speaker: Derek Martin
      Sponsored By: Envigo
      11
      OCT 04, 2022 | 7:00 AM
      Tools & Strategies for Implementing iPSC-based Cell Models for Neurodegenerative Disease Drug Discovery
      Tools & Strategies for Implementing iPSC-based Cell Models for...
      Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
      Speaker: Benjamin Schmid , Peter Reinhardt
      Sponsored By: Bioneer A/S
      13
      SEP 29, 2022 | 7:00 AM
      Multidimensional Approach to Decoding the Mysteries of Animal Development
      Multidimensional Approach to Decoding the Mysteries of Animal...
      Date: September 29, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Development and evolution are controlled, to a large degree, by regions of genomic DNA called enhancers that encode...
      Speaker: Justin Crocker
      Sponsored By: GenScript
      7
      SEP 08, 2022 | 6:00 AM
      Covid Testing Challenges And Opportunities;  A Picture is Worth a Thousand Words
      Covid Testing Challenges And Opportunities; A Picture is Worth...
      Since its discovery in late 2019 the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global pandemic of coronavirus disease 2019 (COVID-19). As of July of 2022, mo...
      Speaker: Irene Bosch, PhD
      Presented at: Microbiology Week Virtual Event Series 2022
      3
      JUL 28, 2022 | 6:00 AM
      Take action against viral HCV by leveraging screening programs and HCV Ag
      Take action against viral HCV by leveraging screening programs...
      Date: July 28, 2022 Time: 6:00am (PDT), 9:00am (EDT) Hepatitis B and C continues to be a leading cause of global morbidity and mortality, resulting in 1.1 million deaths and 3 million new in...
      Speaker: Dr. Mia Biondi
      Sponsored By: Abbott Diagnostics
      18
      MAY 31, 2022 | 9:00 AM
      Interrogate tumor-immune interactions in AML patients receiving immune checkpoint inhibitor
      Interrogate tumor-immune interactions in AML patients receiving...
      Date: May 31, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Introducing Nanostring’s latest spatial platform, CosMx Spatial Molecular Imager (SMI). Offering high-plex, multiomi...
      Speaker: Vikram Devgan, PhD, MBA , Dr. Chen Zhao
      Sponsored By: NanoString Technologies
      14
      MAY 04, 2022 | 6:00 AM
      Keynote Presentation: Toward Universal Coronavirus Vaccines: From Concept to Clinic
      Keynote Presentation: Toward Universal Coronavirus Vaccines: From...
      The need for next-generation, broadly protective coronavirus vaccines is underscored by the accelerated pace at which human coronaviruses have been emerging, the evolution of the current pan...
      Speaker: Kayvon Modjarrad, MD, PhD
      Presented at: Coronavirus Series
      3
      MAY 04, 2022 | 5:30 AM
      Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
      Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
      Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
      Speaker: Tracy Fischer, PhD
      Presented at: Coronavirus Series
      2
      APR 06, 2022 | 5:30 AM
      Optimising Cell Line Development for Bioprocessing
      Optimising Cell Line Development for Bioprocessing
      In the last decades, the upstream processing in biopharma industry has been revolutionized regarding the production of bioactive materials such as monoclonal antibodies, proteins and biother...
      Speaker: Sami Ullah, PhD
      Presented at: Bioprocessing Virtual Event Series 2022
      4
      MAR 10, 2022 | 1:30 PM
      Utilization of the Luminex Platform to Discover and Develop Dual Toll-like Receptor 2 and 9 Antagonists for the Treatment of Neurodegenerative Diseases
      Utilization of the Luminex Platform to Discover and Develop Dual...
      Neuropore Therapies is discovering and developing novel small molecule disease-modifying therapeutics to treat patients with neurodegenerative diseases, including Parkinson’s disease a...
      Speaker: Diana L. Price, PhD
      Presented at: Neuroscience Virtual Event Series 2022
      Sponsored By: Luminex - A DiaSorin Company
      1
      FEB 24, 2022 | 9:00 AM
      Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate Detection and Interpretation of Cytokine Expression
      Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate...
      Date: February 24, 2021 Time: 9:00am (PST), 12:00pm (EST) Cytokine profiling is a valuable tool used in preclinical research for monitoring an immune response and cell signaling pathways dur...
      Speaker: Laura Hocum Stone , Scott Hunter Oppler
      Sponsored By: ACD - A Bio-Techne Brand
      7
      FEB 23, 2022 | 11:55 PM
      Development and Characterization of an In Vitro Integrated Organ Platform for the Evaluation of Pharmacokinetic and Toxicologic Effects of Drugs and Chemicals
      Development and Characterization of an In Vitro Integrated Organ...
      The quest for alternatives to animal safety testing has fueled the development, characterization, and validation of many new technologies. There have been advances in cell and tissue models...
      Speaker: James McKim, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      3
      DEC 09, 2021 | 8:00 AM
      Reprogramming human regulatory T cell specificity with a novel anti-HLA-A2 chimeric antigen receptor
      Reprogramming human regulatory T cell specificity with a novel...
      Date: December 9, 2021 Time: 8:00am (PDT), 11:00am (EDT) Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donorderived human leukocyte antigen (H...
      Speaker: Leonardo Ferreira
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      DEC 07, 2021 | 10:00 AM
      An overview of a novel RNAscope™ in situ hybridization technology, and applications in pathology of animal models
      An overview of a novel RNAscope™ in situ hybridization technology,...
      Date: December 07, 2021 Time: 10:00am (PST) The RNAscope™ technology allows high sensitivity and spatial resolution providing pivotal single-cell information to gain better insights in...
      Speaker: Anushka Dikshit, PhD , Sebastien Monette
      Sponsored By: ACD, a Bio-Techne brand
      1
    SEP 13, 2023 | 9:00 AM
    Gibco Cell Culture Heroes - Guy Kunzmann - Investigating the conditionally essential role of protein UFMylation in proliferating human cells
    Gibco Cell Culture Heroes - Guy Kunzmann - Investigating the conditionally...
    CRISPR-based forward genetic screens can be used to identify essential genes in proliferating human cell lines. Although environmental factors also influence gene essentiality, most CRISPR-b...
    Speaker: Guy Kunzmann, BS.
    Sponsored By: Thermo Fisher Scientific
    13
    JUN 15, 2023 | 10:00 AM
    Expanding the frontiers of gene editing: the role of genotypic confirmation
    Expanding the frontiers of gene editing: the role of genotypic...
    Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    18
    JUN 14, 2023 | 8:00 AM
    Expanding the frontiers of gene editing: the role of genotypic confirmation
    Expanding the frontiers of gene editing: the role of genotypic...
    Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    15
    MAY 09, 2023 | 1:00 PM
    Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating the biology of cell-in-cell structures in the human liver using a range of microscopy modalities
    Gibco Cell Culture Heroes - Scott Philip Davies, PhD - Investigating...
    Date: May 09, 2023 Time: 5:00am (PDT), 8:00pm (EDT), 2:00pm (CEST) Advances in high content imaging (HCI) have improved the use of cell culture to make a large number of comparisons within i...
    Speaker: Scott Davies, PhD, MRes, MSci
    Sponsored By: Thermo Fisher Scientific
    10
    MAR 08, 2023 | 8:00 AM
    Considerations to Limit Off-Target Edits in your Gene Editing Experiments
    Considerations to Limit Off-Target Edits in your Gene Editing...
    Date: March 08, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the geno...
    Speaker: Kevin Pridham
    Sponsored By: Thermo Fisher Scientific
    12
     
     
  • MAR 08, 2023 | 7:30 AM
    Keynote Presentation: Improving Research Translation in Dementia: Humanized Mouse Models, Cognition and Imaging with Live Q&A
    Keynote Presentation: Improving Research Translation in Dementia:...
    Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
    Speaker: Marco A.M. Prado, Pharm, MSc, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    4
    FEB 22, 2023 | 5:30 AM
    Bridging the Gap - How Human Microphysiological Systems Improve the Translatability of NASH Drug Discovery
    Bridging the Gap - How Human Microphysiological Systems Improve...
    Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
    Speaker: Raul Silva
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    2
    NOV 15, 2022 | 9:00 AM
    Reverse engineering the human heart with pluripotent stem cells
    Reverse engineering the human heart with pluripotent stem cells
    Date: November 15, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Recent advances in stem cell technologies, synthetic development and organoid biology are enabling us to create more a...
    Speaker: Aitor Aguirre, PhD
    Sponsored By: BPS Bioscience
    14
    NOV 08, 2022 | 11:00 AM
    Thinking translational: Things to consider in CAR T cell workflows
    Thinking translational: Things to consider in CAR T cell workflows
    Date: November 08, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CET) Developing safe and effective CAR T cell therapies is a challenging task. That’s why thinking translational earl...
    Speaker: Robert Davies
    Sponsored By: Miltenyi Biotec
    9
    NOV 01, 2022 | 10:00 AM
    Flow cytometric gene mutation assay, made possible by immunomagnetic separation, achieves OECD regulatory status
    Flow cytometric gene mutation assay, made possible by immunomagnetic...
    Date: November 01, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 6:00pm (CET) Our laboratory developed the Pig-a gene mutation assay as a means to simply and reliably evaluate the potential mutage...
    Speaker: Jeffrey Bemis, Ph.D. , Joe Ostrand, Ph.D.
    Sponsored By: Miltenyi Biotec
    11
     
     
  • OCT 05, 2022 | 11:00 AM
    Understanding Fiber in Laboratory Rodent Diets - Definitions, Measurements, and Adjustments
    Understanding Fiber in Laboratory Rodent Diets - Definitions,...
    Date: October 05, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEST) The effects of fiber in health and disease is an active subject of research in a range of research areas. Historically...
    Speaker: Derek Martin
    Sponsored By: Envigo
    11
    OCT 04, 2022 | 7:00 AM
    Tools & Strategies for Implementing iPSC-based Cell Models for Neurodegenerative Disease Drug Discovery
    Tools & Strategies for Implementing iPSC-based Cell Models for...
    Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
    Speaker: Benjamin Schmid , Peter Reinhardt
    Sponsored By: Bioneer A/S
    13
    SEP 29, 2022 | 7:00 AM
    Multidimensional Approach to Decoding the Mysteries of Animal Development
    Multidimensional Approach to Decoding the Mysteries of Animal...
    Date: September 29, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Development and evolution are controlled, to a large degree, by regions of genomic DNA called enhancers that encode...
    Speaker: Justin Crocker
    Sponsored By: GenScript
    7
    SEP 08, 2022 | 6:00 AM
    Covid Testing Challenges And Opportunities;  A Picture is Worth a Thousand Words
    Covid Testing Challenges And Opportunities; A Picture is Worth...
    Since its discovery in late 2019 the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global pandemic of coronavirus disease 2019 (COVID-19). As of July of 2022, mo...
    Speaker: Irene Bosch, PhD
    Presented at: Microbiology Week Virtual Event Series 2022
    3
    JUL 28, 2022 | 6:00 AM
    Take action against viral HCV by leveraging screening programs and HCV Ag
    Take action against viral HCV by leveraging screening programs...
    Date: July 28, 2022 Time: 6:00am (PDT), 9:00am (EDT) Hepatitis B and C continues to be a leading cause of global morbidity and mortality, resulting in 1.1 million deaths and 3 million new in...
    Speaker: Dr. Mia Biondi
    Sponsored By: Abbott Diagnostics
    18
     
     
  • MAY 31, 2022 | 9:00 AM
    Interrogate tumor-immune interactions in AML patients receiving immune checkpoint inhibitor
    Interrogate tumor-immune interactions in AML patients receiving...
    Date: May 31, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Introducing Nanostring’s latest spatial platform, CosMx Spatial Molecular Imager (SMI). Offering high-plex, multiomi...
    Speaker: Vikram Devgan, PhD, MBA , Dr. Chen Zhao
    Sponsored By: NanoString Technologies
    14
    MAY 04, 2022 | 6:00 AM
    Keynote Presentation: Toward Universal Coronavirus Vaccines: From Concept to Clinic
    Keynote Presentation: Toward Universal Coronavirus Vaccines: From...
    The need for next-generation, broadly protective coronavirus vaccines is underscored by the accelerated pace at which human coronaviruses have been emerging, the evolution of the current pan...
    Speaker: Kayvon Modjarrad, MD, PhD
    Presented at: Coronavirus Series
    3
    MAY 04, 2022 | 5:30 AM
    Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
    Neuropathology of SARS-CoV-2 Infection in Aged Non-human Primates
    Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
    Speaker: Tracy Fischer, PhD
    Presented at: Coronavirus Series
    2
    APR 06, 2022 | 5:30 AM
    Optimising Cell Line Development for Bioprocessing
    Optimising Cell Line Development for Bioprocessing
    In the last decades, the upstream processing in biopharma industry has been revolutionized regarding the production of bioactive materials such as monoclonal antibodies, proteins and biother...
    Speaker: Sami Ullah, PhD
    Presented at: Bioprocessing Virtual Event Series 2022
    4
    MAR 10, 2022 | 1:30 PM
    Utilization of the Luminex Platform to Discover and Develop Dual Toll-like Receptor 2 and 9 Antagonists for the Treatment of Neurodegenerative Diseases
    Utilization of the Luminex Platform to Discover and Develop Dual...
    Neuropore Therapies is discovering and developing novel small molecule disease-modifying therapeutics to treat patients with neurodegenerative diseases, including Parkinson’s disease a...
    Speaker: Diana L. Price, PhD
    Presented at: Neuroscience Virtual Event Series 2022
    Sponsored By: Luminex - A DiaSorin Company
    1
     
     
  • FEB 24, 2022 | 9:00 AM
    Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate Detection and Interpretation of Cytokine Expression
    Optimizing Cytokine Analysis-Choosing the Right Assay for Accurate...
    Date: February 24, 2021 Time: 9:00am (PST), 12:00pm (EST) Cytokine profiling is a valuable tool used in preclinical research for monitoring an immune response and cell signaling pathways dur...
    Speaker: Laura Hocum Stone , Scott Hunter Oppler
    Sponsored By: ACD - A Bio-Techne Brand
    7
    FEB 23, 2022 | 11:55 PM
    Development and Characterization of an In Vitro Integrated Organ Platform for the Evaluation of Pharmacokinetic and Toxicologic Effects of Drugs and Chemicals
    Development and Characterization of an In Vitro Integrated Organ...
    The quest for alternatives to animal safety testing has fueled the development, characterization, and validation of many new technologies. There have been advances in cell and tissue models...
    Speaker: James McKim, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    3
    DEC 09, 2021 | 8:00 AM
    Reprogramming human regulatory T cell specificity with a novel anti-HLA-A2 chimeric antigen receptor
    Reprogramming human regulatory T cell specificity with a novel...
    Date: December 9, 2021 Time: 8:00am (PDT), 11:00am (EDT) Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donorderived human leukocyte antigen (H...
    Speaker: Leonardo Ferreira
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    DEC 07, 2021 | 10:00 AM
    An overview of a novel RNAscope™ in situ hybridization technology, and applications in pathology of animal models
    An overview of a novel RNAscope™ in situ hybridization technology,...
    Date: December 07, 2021 Time: 10:00am (PST) The RNAscope™ technology allows high sensitivity and spatial resolution providing pivotal single-cell information to gain better insights in...
    Speaker: Anushka Dikshit, PhD , Sebastien Monette
    Sponsored By: ACD, a Bio-Techne brand
    1
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