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    Engineering T cells

    Engineering T cells is a broad description of techniques used to modify a T cells obtained from a patient or healthy donor. T cells are a subset of immune cells responsible for targeting and killing tumor cells. Once harvested from a patient or donor, the T cells can be engineered in a laboratory making them better capable of killing a specific tumor. Examples of adoptive cell therapies using engineered T cells are T cell receptor (TCR)-engineered T cells and chimeric antigen receptor (CAR) T cells.

    Trending News

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      Millions of people around the world have been infected with the coronavirus called SARS-CoV-2, which causes COVID-19. Th ...
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      JUL 03, 2020
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      A Gut Pathogen Moves With Help From Its Environment
      A Gut Pathogen Moves With Help From Its Environment
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      JUN 11, 2020
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      JUN 08, 2020
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      How Cancer Cells Use Inflammation as a Shield Against Viruses
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      JUN 03, 2020
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      MAY 25, 2020
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      Rewrite the Books: Retinoic Acid Does Not Trigger Meiosis
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      MAY 22, 2020
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      MAY 17, 2020
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      MAY 10, 2020
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      MAY 07, 2020
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      APR 27, 2020
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      APR 26, 2020
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      APR 26, 2020
      Cell & Molecular Biology
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      APR 23, 2020
      Chemistry & Physics
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      "Green" Ammonia: Out of Laundry Room, Into Engine Room
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      APR 22, 2020
      Immunology
      Scientists Engineer Custom Antiviral Receptors to Fight COVID-19
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      APR 20, 2020
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      APR 13, 2020
      Cancer
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      The Unexpected Role of Mono in Cancer Progression
      In the past, the go-to drugs have always been small molecules. These small molecules would interact with the cell and ac ...
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      APR 13, 2020
      Cell & Molecular Biology
      Getting Closer to Making Heparin in Cells
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      APR 02, 2020
      Cell & Molecular Biology
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    JUL 03, 2020
    Microbiology
    Oxford COVID-19 Vaccine Enters Phase 3 Clinical Trials
    Oxford COVID-19 Vaccine Enters Phase 3 Clinical Trials
    Millions of people around the world have been infected with the coronavirus called SARS-CoV-2, which causes COVID-19. Th ...
    Written By: Carmen Leitch
    1
    JUL 03, 2020
    Cell & Molecular Biology
    A Gut Pathogen Moves With Help From Its Environment
    A Gut Pathogen Moves With Help From Its Environment
    Campylobacter jejuni is a foodborne bacterial pathogen that causes millions of cases of food poisoning each year.
    Written By: Carmen Leitch
    1
    JUN 11, 2020
    Genetics & Genomics
    Restoring Hearing by Editing Only One Base of a Gene
    Restoring Hearing by Editing Only One Base of a Gene
    Errors in genes can cause serious diseases. Some of those errors are large, while others are due to a change in only one ...
    Written By: Carmen Leitch
    1
    JUN 09, 2020
    Microbiology
    Bacteria Will Commit Suicide to Spare Their Colony
    Bacteria Will Commit Suicide to Spare Their Colony
    In nature, strains of bacteria usually grow in colonies, and together, they are tougher.
    Written By: Carmen Leitch
    2
    JUN 09, 2020
    Immunology
    Peacekeeping Engineered T Cells Restore the Balance in Diabetes
    Peacekeeping Engineered T Cells Restore the Balance in Diabetes
    For patients with type 1 diabetes, hope is around the corner with a new experimental therapy that uses genetically modif ...
    Written By: Tara Fernandes
    1
     
     
  • JUN 08, 2020
    Cell & Molecular Biology
    How Cancer Cells Use Inflammation as a Shield Against Viruses
    How Cancer Cells Use Inflammation as a Shield Against Viruses
    Microorganisms called oncolytic viruses can infect and kill cancer cells while leaving healthy cells alone.
    Written By: Carmen Leitch
    1
    JUN 03, 2020
    Cell & Molecular Biology
    A New Insulin That's Based on Cone Snail Venom
    A New Insulin That's Based on Cone Snail Venom
    Insulin is a hormone that's produced by a specific set of cells in the pancreas, and it functions to regulate blood ...
    Written By: Carmen Leitch
    1
    MAY 25, 2020
    Cell & Molecular Biology
    Rewrite the Books: Retinoic Acid Does Not Trigger Meiosis
    Rewrite the Books: Retinoic Acid Does Not Trigger Meiosis
    Researchers are challenging what we thought we knew about the mechanism of sexual reproduction.
    Written By: Carmen Leitch
    1
    MAY 22, 2020
    Genetics & Genomics
    ALK - The Skinny Gene?
    ALK - The Skinny Gene?
    Some people have to count calories and exercise regularly to be skinny while others can consume whatever they want and n ...
    Written By: Carmen Leitch
    1
    MAY 17, 2020
    Microbiology
    More Research Links ALS to the Microbiome
    More Research Links ALS to the Microbiome
    The community of microorganisms that lives in the gastrointestinal tract has a powerful influence on human health.
    Written By: Carmen Leitch
    2
     
     
  • MAY 10, 2020
    Genetics & Genomics
    Towards a Targeted Elimination of Leukemic Cells
    Towards a Targeted Elimination of Leukemic Cells
    Our blood carries many types of critical cells, including platelets, red blood cells, and white blood cells, which are m ...
    Written By: Carmen Leitch
    2
    MAY 09, 2020
    Clinical & Molecular DX
    Rapid, Efficient COVID-19 Diagnostic Method Relies on Magnetic Beads
    Rapid, Efficient COVID-19 Diagnostic Method Relies on Magnetic Beads
    The pandemic virus SARS-CoV-2 has spread widely, and a lack of testing has been a serious problem.
    Written By: Carmen Leitch
    2
    MAY 07, 2020
    Cell & Molecular Biology
    How the Function of a Critical Immune Cell is Related to Metabolism
    How the Function of a Critical Immune Cell is Related to Metabolism
    This work suggests that it may be possible to dampen autoimmunity or promote an immune attack on cancer through a bioche ...
    Written By: Carmen Leitch
    1
    MAY 03, 2020
    Microbiology
    Understanding How Lyme Disease Persists in the Body
    Understanding How Lyme Disease Persists in the Body
    Lyme disease is a confounding illness that can be difficult to diagnose, and can cause a wide range of serious health pr ...
    Written By: Carmen Leitch
    2
    APR 28, 2020
    Microbiology
    Communities of Microbes Can Form 'Memories'
    Communities of Microbes Can Form 'Memories'
    Microbes can grow in tight clusters called biofilms. These communities are tough, and have some of the same properties a ...
    Written By: Carmen Leitch
    3
     
     
  • APR 27, 2020
    Cell & Molecular Biology
    Cold Foods Don't Taste as Good, Even to Flies
    Cold Foods Don't Taste as Good, Even to Flies
    The deliciousness of a food appeal is about a lot more than just taste.
    Written By: Carmen Leitch
    2
    APR 26, 2020
    Genetics & Genomics
    Does Poor Sleep Lead to Obesity, or is the Opposite True?
    Does Poor Sleep Lead to Obesity, or is the Opposite True?
    For many years, researchers have been aware of the link between obesity and poor sleep or a lack of sleep. But what come ...
    Written By: Carmen Leitch
    2
    APR 26, 2020
    Cell & Molecular Biology
    Researchers Remotely Trigger the Release of Hormones
    Researchers Remotely Trigger the Release of Hormones
    It may one day be possible to treat hormone-related diseases using this method.
    Written By: Carmen Leitch
    2
    APR 23, 2020
    Chemistry & Physics
    "Green" Ammonia: Out of Laundry Room, Into Engine Room
    "Green" Ammonia: Out of Laundry Room, Into Engine Room
    The Paris Agreement outlines a series of measures for our society to adopt so that we can reduce greenhouse gas emission ...
    Written By: Daniel Duan
    1
    APR 22, 2020
    Immunology
    Scientists Engineer Custom Antiviral Receptors to Fight COVID-19
    Scientists Engineer Custom Antiviral Receptors to Fight COVID-19
    The best offense may be a good defense in the fight against COVID-19. Researchers from the Duke-NUS Medical School are e ...
    Written By: Kara Marker
    1
     
     
  • APR 20, 2020
    Genetics & Genomics
    Advances in Gene Therapy for Neurons
    Advances in Gene Therapy for Neurons
    New research may aid in the development of gene therapies for diseases like Alzheimer's and Parkinson's.
    Written By: Carmen Leitch
    1
    APR 13, 2020
    Cancer
    The Unexpected Role of Mono in Cancer Progression
    The Unexpected Role of Mono in Cancer Progression
    In the past, the go-to drugs have always been small molecules. These small molecules would interact with the cell and ac ...
    Written By: Jasper Cantrell
    1
    APR 13, 2020
    Cell & Molecular Biology
    Getting Closer to Making Heparin in Cells
    Getting Closer to Making Heparin in Cells
    While heparin is the most commonly prescribed drug in hospitals, we have to extract it from pig intestines, which is fra ...
    Written By: Carmen Leitch
    1
    APR 02, 2020
    Cell & Molecular Biology
    Cooling Injured Brain Cells Can Aid Recovery
    Cooling Injured Brain Cells Can Aid Recovery
    According to the CDC, in 2014 there were around 2.87 million incidences of TBI-related ER visits.
    Written By: Carmen Leitch
    1
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