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    Genome Sciences

    Genome science refers to the study of the genome, and organism's complete set of DNA which includes all of its genes. Genome constrasts with genetics, the latter of which refers to the study of one specific gene and their role in inheritance.

    Webinars

    • SEP 30, 2020 | 12:00 AM
      Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
      Elucidation of remdesivir cytotoxicity pathways through genome-wide...
      The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
      Speaker: Minja Velimirovic, MSc, PhD Candidate
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
      CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
      Speaker: Jonas Korlach, PhD
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
      Speaker: Adam Ameur
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      An Automated Integrated Multiple Assay Platform utilizing CRISPR-based Transistors for CRISPR Quality Control Applications
      An Automated Integrated Multiple Assay Platform utilizing CRISPR-based...
      Learning Objectives: 1. Using an optics- and label-free approach to CRISPR research 2. Explain current approaches to selecting the most robust gRNA for CRISPR assays 3. The opportunities tha...
      Speaker: Kiana Aran, PhD
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 PM
      Mass Cytometry in Translational Research: Session II
      Mass Cytometry in Translational Research: Session II
      B cells and tertiary lymphoid structures (TLS) promote immunotherapy response 1:00–1:30 pm PDT Presented By: Rafet Basar, MD...
      Speaker: Handan Xiang, PhD , Pei-Yu Chen, PhD , Hiranmayi Ravichandran, MS , Rafet Basar, MD , Amir Horowitz, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      2
      SEP 23, 2020 | 10:30 AM
      New Insights Gained with Imaging Mass Cytometry
      New Insights Gained with Imaging Mass Cytometry
      Speaker TBD 10:30–10:50 am PDT Exploring the immune tumor microenvironment of hepatocellular carcinoma with Imaging Mass Cytometry™ 10:50 am–11:10 am PDT Presented By: Won...
      Speaker: Won Jin Ho, MD , Melissa B. Davis, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 23, 2020 | 6:00 AM
      Welcome and Opening Remarks
      Welcome and Opening Remarks
      ...
      Speaker: Chris Linthwaite , Andrew Quong, PhD , Alex Cherkassky, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 23, 2020 | 12:00 AM
      Deep learning to integrate histology with spatial transcriptomics
      Deep learning to integrate histology with spatial transcriptomics
      I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
      Speaker: James Zou
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 AM
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers...
      GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
      Speaker: Kit Fuhrman
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 17, 2020 | 3:30 PM
      SARS-CoV-2 Testing Today and a New Serology Approach For High Throughput Screening
      SARS-CoV-2 Testing Today and a New Serology Approach For High...
      Richard Hughes: New immunogenicity strategies to meet the needs of a developing pandemic Shortly after the COVID-19 pandemic began, the subject of serological testing for anti-viral antibodi...
      Speaker: Russell Garlick, PhD , Richard Hughes , Joel Lefferts, PhD, HCLD, DABCC
      Presented at: Coronavirus Series
      Sponsored By: LGC Seracare
      1
      SEP 17, 2020 | 11:00 AM
      Host and Viral Transcriptomes During COVID-19 Infection
      Host and Viral Transcriptomes During COVID-19 Infection
      In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
      Speaker: Christopher E. Mason, PhD
      Presented at: Coronavirus Series
      3
      SEP 17, 2020 | 1:30 PM
      Decoding the Variance in Intracellular Organization in Human Stem Cells
      Decoding the Variance in Intracellular Organization in Human Stem...
      The Allen Institute for Cell Science is generating a state space of stem cell signatures. The goal is to understand cell organization, identify cell states, and elucidate how cells transitio...
      Speaker: Susanne Rafelski, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      1
      SEP 17, 2020 | 8:00 AM
      Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform
      Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9...
      DATE: September 17, 2020 TIME: 8:00am PT CRISPR-Cas9 has tremendous potential as a therapeutic tool for treating human diseases. However, prolonged expression of the nuclease and gRNA from v...
      Speaker: Peter Gee, Ph.D.
      Sponsored By: MaxCyte®
      6
      SEP 17, 2020 | 12:00 AM
      The detection, characterization, and surveillance of the SARS-CoV-2 viral genome using hybridization capture-based NGS assay
      The detection, characterization, and surveillance of the SARS-CoV-2...
      As the spread of infectious diseases, current pandemic, and growing antimicrobial resistance (AMR) continues globally, next-generation sequencing (NGS) became a tool to diagnose infectious d...
      Speaker: Dorottya Nagy-Szakal, MD PhD
      Presented at: Coronavirus Series
      1
      SEP 16, 2020 | 11:00 AM
      How to Limit Patient Harm from Erroneous Results, QC Strategies Based on Risk Management
      How to Limit Patient Harm from Erroneous Results, QC Strategies...
      Quality Control design has for many years been focused around instrument performance. But with the new risk management approaches emerging the focus is now moving to the risk of erroneous re...
      Speaker: John Yundt-Pacheco, MSCS
      Presented at: A Bio-Rad Quality Control Virtual Conference
      12 2
      SEP 16, 2020 | 9:00 AM
      Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
      Deep multi-omic phenotyping of biospecimens for immuno-oncology...
      Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
      Speaker: Dr. Shawn Fahl
      Sponsored By: Miltenyi Biotec
      11
      SEP 11, 2020 | 8:00 AM
      Implementing a World-Class Clinical Pharmacogenomics Service
      Implementing a World-Class Clinical Pharmacogenomics Service
      DATE: September 11, 2020 TIME: 08:00am PT, 11:00pm ET This is the third topic in the webinar series on ‘ Predictive Genomics for Population & Personalized Health ’. Pharmacog...
      Speaker: Dr. Hyun Kim
      Sponsored By: Thermo Fisher Scientific/Gibco
      8 2
      SEP 10, 2020 | 12:00 PM
      Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
      Bacterial strain typing and genomics characterization of multi-drug...
      In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
      Speaker: Jonathan Jacobs, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      SEP 10, 2020 | 11:00 AM
      Optimizing the extraction of human microbiome samples
      Optimizing the extraction of human microbiome samples
      Learning Objectives: 1. Understand the challenges of extracting DNA from human samples for microbiome analysis, and learn about the best technologies for accomplishing this 2. Learn about pr...
      Speaker: Dominic O'Neil, MS, MBA
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      SEP 10, 2020 | 10:00 AM
      Keynote Presentation: Squeezing out understanding from sequences: Genome to Phenome Connections in Viruses of Microbes
      Keynote Presentation: Squeezing out understanding from sequences:...
      Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...
      Speaker: K. Eric Wommack
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
      A novel strategy to investigate longitudinal changes within the...
      Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
      Speaker: Candice M. Brown, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      Identifying and linking antimicrobial resistance genes in metagenomes with new DNA sequencing technologies
      Identifying and linking antimicrobial resistance genes in metagenomes...
      The transfer of antimicrobial resistance genes (ARG) to pathogenic microbes is a major concern in modern medicine. Antibiotic therapies are often rendered ineffective by horizontal acquisiti...
      Speaker: Derek Bickhart, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      SEP 10, 2020 | 12:00 AM
      Precision infectious disease discovery using next-generation sequencing and AI to provide insights into respiratory, urine, and stool samples
      Precision infectious disease discovery using next-generation sequencing...
      Lessons around leveraging high-complexity next-generation sequencing tests for precision infectious disease discovery to guide patient treatment and improve health outcomes. Learning Objecti...
      Speaker: Niamh O'Hara, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
    SEP 30, 2020 | 12:00 AM
    Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
    Elucidation of remdesivir cytotoxicity pathways through genome-wide...
    The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
    Speaker: Minja Velimirovic, MSc, PhD Candidate
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 30, 2020 | 12:00 AM
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
    CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
    Speaker: Jonas Korlach, PhD
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
    Speaker: Adam Ameur
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    An Automated Integrated Multiple Assay Platform utilizing CRISPR-based Transistors for CRISPR Quality Control Applications
    An Automated Integrated Multiple Assay Platform utilizing CRISPR-based...
    Learning Objectives: 1. Using an optics- and label-free approach to CRISPR research 2. Explain current approaches to selecting the most robust gRNA for CRISPR assays 3. The opportunities tha...
    Speaker: Kiana Aran, PhD
    Presented at: CRISPR Virtual Event Series 2020
    1
     
     
  • SEP 23, 2020 | 12:00 PM
    Mass Cytometry in Translational Research: Session II
    Mass Cytometry in Translational Research: Session II
    B cells and tertiary lymphoid structures (TLS) promote immunotherapy response 1:00–1:30 pm PDT Presented By: Rafet Basar, MD...
    Speaker: Handan Xiang, PhD , Pei-Yu Chen, PhD , Hiranmayi Ravichandran, MS , Rafet Basar, MD , Amir Horowitz, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    2
    SEP 23, 2020 | 10:30 AM
    New Insights Gained with Imaging Mass Cytometry
    New Insights Gained with Imaging Mass Cytometry
    Speaker TBD 10:30–10:50 am PDT Exploring the immune tumor microenvironment of hepatocellular carcinoma with Imaging Mass Cytometry™ 10:50 am–11:10 am PDT Presented By: Won...
    Speaker: Won Jin Ho, MD , Melissa B. Davis, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 23, 2020 | 6:00 AM
    Welcome and Opening Remarks
    Welcome and Opening Remarks
    ...
    Speaker: Chris Linthwaite , Andrew Quong, PhD , Alex Cherkassky, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 23, 2020 | 12:00 AM
    Deep learning to integrate histology with spatial transcriptomics
    Deep learning to integrate histology with spatial transcriptomics
    I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
    Speaker: James Zou
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 23, 2020 | 12:00 AM
    GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)
    GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers...
    GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
    Speaker: Kit Fuhrman
    Presented at: Cell Biology Virtual Event Series 2020
    1
     
     
  • SEP 17, 2020 | 3:30 PM
    SARS-CoV-2 Testing Today and a New Serology Approach For High Throughput Screening
    SARS-CoV-2 Testing Today and a New Serology Approach For High...
    Richard Hughes: New immunogenicity strategies to meet the needs of a developing pandemic Shortly after the COVID-19 pandemic began, the subject of serological testing for anti-viral antibodi...
    Speaker: Russell Garlick, PhD , Richard Hughes , Joel Lefferts, PhD, HCLD, DABCC
    Presented at: Coronavirus Series
    Sponsored By: LGC Seracare
    1
    SEP 17, 2020 | 11:00 AM
    Host and Viral Transcriptomes During COVID-19 Infection
    Host and Viral Transcriptomes During COVID-19 Infection
    In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
    Speaker: Christopher E. Mason, PhD
    Presented at: Coronavirus Series
    3
    SEP 17, 2020 | 1:30 PM
    Decoding the Variance in Intracellular Organization in Human Stem Cells
    Decoding the Variance in Intracellular Organization in Human Stem...
    The Allen Institute for Cell Science is generating a state space of stem cell signatures. The goal is to understand cell organization, identify cell states, and elucidate how cells transitio...
    Speaker: Susanne Rafelski, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    1
    SEP 17, 2020 | 8:00 AM
    Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform
    Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9...
    DATE: September 17, 2020 TIME: 8:00am PT CRISPR-Cas9 has tremendous potential as a therapeutic tool for treating human diseases. However, prolonged expression of the nuclease and gRNA from v...
    Speaker: Peter Gee, Ph.D.
    Sponsored By: MaxCyte®
    6
    SEP 17, 2020 | 12:00 AM
    The detection, characterization, and surveillance of the SARS-CoV-2 viral genome using hybridization capture-based NGS assay
    The detection, characterization, and surveillance of the SARS-CoV-2...
    As the spread of infectious diseases, current pandemic, and growing antimicrobial resistance (AMR) continues globally, next-generation sequencing (NGS) became a tool to diagnose infectious d...
    Speaker: Dorottya Nagy-Szakal, MD PhD
    Presented at: Coronavirus Series
    1
     
     
  • SEP 16, 2020 | 11:00 AM
    How to Limit Patient Harm from Erroneous Results, QC Strategies Based on Risk Management
    How to Limit Patient Harm from Erroneous Results, QC Strategies...
    Quality Control design has for many years been focused around instrument performance. But with the new risk management approaches emerging the focus is now moving to the risk of erroneous re...
    Speaker: John Yundt-Pacheco, MSCS
    Presented at: A Bio-Rad Quality Control Virtual Conference
    12 2
    SEP 16, 2020 | 9:00 AM
    Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
    Deep multi-omic phenotyping of biospecimens for immuno-oncology...
    Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
    Speaker: Dr. Shawn Fahl
    Sponsored By: Miltenyi Biotec
    11
    SEP 11, 2020 | 8:00 AM
    Implementing a World-Class Clinical Pharmacogenomics Service
    Implementing a World-Class Clinical Pharmacogenomics Service
    DATE: September 11, 2020 TIME: 08:00am PT, 11:00pm ET This is the third topic in the webinar series on ‘ Predictive Genomics for Population & Personalized Health ’. Pharmacog...
    Speaker: Dr. Hyun Kim
    Sponsored By: Thermo Fisher Scientific/Gibco
    8 2
    SEP 10, 2020 | 12:00 PM
    Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
    Bacterial strain typing and genomics characterization of multi-drug...
    In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
    Speaker: Jonathan Jacobs, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
    SEP 10, 2020 | 11:00 AM
    Optimizing the extraction of human microbiome samples
    Optimizing the extraction of human microbiome samples
    Learning Objectives: 1. Understand the challenges of extracting DNA from human samples for microbiome analysis, and learn about the best technologies for accomplishing this 2. Learn about pr...
    Speaker: Dominic O'Neil, MS, MBA
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
     
     
  • SEP 10, 2020 | 10:00 AM
    Keynote Presentation: Squeezing out understanding from sequences: Genome to Phenome Connections in Viruses of Microbes
    Keynote Presentation: Squeezing out understanding from sequences:...
    Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...
    Speaker: K. Eric Wommack
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 AM
    A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
    A novel strategy to investigate longitudinal changes within the...
    Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
    Speaker: Candice M. Brown, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 AM
    Identifying and linking antimicrobial resistance genes in metagenomes with new DNA sequencing technologies
    Identifying and linking antimicrobial resistance genes in metagenomes...
    The transfer of antimicrobial resistance genes (ARG) to pathogenic microbes is a major concern in modern medicine. Antibiotic therapies are often rendered ineffective by horizontal acquisiti...
    Speaker: Derek Bickhart, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    4
    SEP 10, 2020 | 12:00 AM
    Precision infectious disease discovery using next-generation sequencing and AI to provide insights into respiratory, urine, and stool samples
    Precision infectious disease discovery using next-generation sequencing...
    Lessons around leveraging high-complexity next-generation sequencing tests for precision infectious disease discovery to guide patient treatment and improve health outcomes. Learning Objecti...
    Speaker: Niamh O'Hara, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
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