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    PI3K

    Phosphoinositide 3-kinase (PI3K) describes a family of enzymes required for a variety of cellular functions. PI3K pathways are important for processes, including cellular growth, proliferation, differentiation, and intracellular trafficking.

    What's Popular in PI3K

    Trending News

    • MAY 18, 2023
      Cancer
      Progress Towards Developing Therapies to Prevent Brain Metastases
      Progress Towards Developing Therapies to Prevent Brain Metastases
      Metastatic cancer occurs when tumor cells spread from the original (or primary) cancer site to a distant location.  ...
      Written By: Katie Kokolus
      4
      APR 15, 2023
      Drug Discovery & Development
      Dietary Supplement Combats Drug Resistance in Advanced Breast Cancer
      Dietary Supplement Combats Drug Resistance in Advanced Breast Cancer
      Dietary supplement N-acetylcysteine increases the sensitivity of cancers to a treatment for advanced breast cancer. The ...
      Written By: Annie Lennon
      3
      APR 02, 2023
      Drug Discovery & Development
      For the first time in history, PASLI Disease has an FDA approved treatment: leniolisib
      For the first time in history, PASLI Disease has an FDA approved treatment: leniolisib
      For the first time in history, PASLI Disease has an FDA approved treatment: leniolisib  Activated PI3K Delta Syndro ...
      Written By: Greta Anne
      3
      MAY 10, 2022
      Immunology
      A Failed Immunotherapy Trial Leads to a Crucial Discovery
      A Failed Immunotherapy Trial Leads to a Crucial Discovery
      Immunotherapies, which boost a patient's immune system so it's better at fighting cancer, have been a game-chang ...
      Written By: Carmen Leitch
      4
      MAY 28, 2021
      Genetics & Genomics
      Some Biofilms Seem to Activate Cancer Genes
      Some Biofilms Seem to Activate Cancer Genes
      New research assessed bacterial and fungal biofilms, tenacious microbial communities that are tougher than small groups ...
      Written By: Carmen Leitch
      1
    MAY 18, 2023
    Cancer
    Progress Towards Developing Therapies to Prevent Brain Metastases
    Progress Towards Developing Therapies to Prevent Brain Metastases
    Metastatic cancer occurs when tumor cells spread from the original (or primary) cancer site to a distant location.  ...
    Written By: Katie Kokolus
    4
    APR 15, 2023
    Drug Discovery & Development
    Dietary Supplement Combats Drug Resistance in Advanced Breast Cancer
    Dietary Supplement Combats Drug Resistance in Advanced Breast Cancer
    Dietary supplement N-acetylcysteine increases the sensitivity of cancers to a treatment for advanced breast cancer. The ...
    Written By: Annie Lennon
    3
    APR 02, 2023
    Drug Discovery & Development
    For the first time in history, PASLI Disease has an FDA approved treatment: leniolisib
    For the first time in history, PASLI Disease has an FDA approved treatment: leniolisib
    For the first time in history, PASLI Disease has an FDA approved treatment: leniolisib  Activated PI3K Delta Syndro ...
    Written By: Greta Anne
    3
     
     
    MAY 10, 2022
    Immunology
    A Failed Immunotherapy Trial Leads to a Crucial Discovery
    A Failed Immunotherapy Trial Leads to a Crucial Discovery
    Immunotherapies, which boost a patient's immune system so it's better at fighting cancer, have been a game-chang ...
    Written By: Carmen Leitch
    4
    MAY 28, 2021
    Genetics & Genomics
    Some Biofilms Seem to Activate Cancer Genes
    Some Biofilms Seem to Activate Cancer Genes
    New research assessed bacterial and fungal biofilms, tenacious microbial communities that are tougher than small groups ...
    Written By: Carmen Leitch
    1
    JUN 04, 2020
    Cancer
    Inhibiting the Signals Critical for Cancer Growth in Merkel Cell Carcinoma
    Inhibiting the Signals Critical for Cancer Growth in Merkel Cell Carcinoma
    Merkel Cell Carcinoma (MCC) is a highly aggressive cancer of the skin. It is characterized by a high recurrence rate and ...
    Written By: Jasper Cantrell
    1
    MAY 28, 2020
    Cancer
    The Oncogenic Hazard of a Potential Alzheimer's Treatment
    The Oncogenic Hazard of a Potential Alzheimer's Treatment
    Breast cancer remains one of the most common cancers around the world. Triple-Negative Breast Cancer (TNBC) is a sub-typ ...
    Written By: Jasper Cantrell
    1
    APR 21, 2020
    Drug Discovery & Development
    Classic Chemotherapeutic Repurposed for Treating Leukemia
    Classic Chemotherapeutic Repurposed for Treating Leukemia
    Researchers were seeking a promising new strategy to challenge drug resistance in leukemia. They found that targeted low ...
    Written By: Nouran Amin
    1
    APR 04, 2020
    Cancer
    Unique Cancer Mutation Hijacks Nearby Signaling Pathway
    Unique Cancer Mutation Hijacks Nearby Signaling Pathway
      In cancer, tyrosine kinase mutations are quite common. MET is one such example that normally binds its native lig ...
    Written By: Jasper Cantrell
    1
    See More
    PI3K
    Trending News
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    Webinars

    • JUN 02, 2021 | 10:30 AM
      Keynote Presentation: New Checkpoints and Biomarkers
      Keynote Presentation: New Checkpoints and Biomarkers
      Learning Objectives: 1. Understand how the outcome of PD-1 blockade is a summation of increased Teffector activity and increased Treg suppressive activity 2. Explain how PD-1 blockade leads...
      Speaker: Gordon Freeman, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2021
      2
      OCT 07, 2020 | 12:00 AM
      Oncogene additivity in the PI3K pathway in cancer
      Oncogene additivity in the PI3K pathway in cancer
      Activating mutations in PIK3CA are frequent in human breast cancer, and phosphoinositide 3-kinase alpha (PI3Kα) inhibitors have been approved for therapy. To characterize determinants...
      Speaker: Neil Vasan, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 23, 2020 | 10:30 AM
      Practical Mass Cytometry
      Practical Mass Cytometry
      On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
      Speaker: Tim Bushnell, PhD, MBA , Gerd Haga Bringeland, MD, PhD , Greg Hopkins, BS
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      2
      MAY 20, 2020 | 1:15 PM
      GeoMx® Protein Offerings: Fully validated antibodies to meet your spatial profiling needs
      GeoMx® Protein Offerings: Fully validated antibodies to meet your...
      With over 200 validated antibodies and the option to add custom antibodies, the GeoMx DSP protein portfolio offers options to fit a wide range of spatial profiling application needs. NanoStr...
      Speaker: Jenny Cronin, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      6
    JUN 02, 2021 | 10:30 AM
    Keynote Presentation: New Checkpoints and Biomarkers
    Keynote Presentation: New Checkpoints and Biomarkers
    Learning Objectives: 1. Understand how the outcome of PD-1 blockade is a summation of increased Teffector activity and increased Treg suppressive activity 2. Explain how PD-1 blockade leads...
    Speaker: Gordon Freeman, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2021
    2
    OCT 07, 2020 | 12:00 AM
    Oncogene additivity in the PI3K pathway in cancer
    Oncogene additivity in the PI3K pathway in cancer
    Activating mutations in PIK3CA are frequent in human breast cancer, and phosphoinositide 3-kinase alpha (PI3Kα) inhibitors have been approved for therapy. To characterize determinants...
    Speaker: Neil Vasan, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    2
     
     
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 23, 2020 | 10:30 AM
    Practical Mass Cytometry
    Practical Mass Cytometry
    On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
    Speaker: Tim Bushnell, PhD, MBA , Gerd Haga Bringeland, MD, PhD , Greg Hopkins, BS
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    2
    MAY 20, 2020 | 1:15 PM
    GeoMx® Protein Offerings: Fully validated antibodies to meet your spatial profiling needs
    GeoMx® Protein Offerings: Fully validated antibodies to meet your...
    With over 200 validated antibodies and the option to add custom antibodies, the GeoMx DSP protein portfolio offers options to fit a wide range of spatial profiling application needs. NanoStr...
    Speaker: Jenny Cronin, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    6
    JAN 25, 2018 | 8:00 AM
    WEBINAR:  Understanding Immunosuppressive Myeloid Cells and Immunotherapy using Proteome Profilerâ„¢ Arrays
    WEBINAR: Understanding Immunosuppressive Myeloid Cells and Immunotherapy...
    DATE: January 25, 2018TIME:  8:00AM PST, 10:00AM CSTProstate cancer (PCa) is the most common noncutaneous malignancy in men in the US. A significant fraction of advanced PCa treate...
    Speaker: Xin Lu, PhD
    Sponsored By: ACD - A Bio-Techne Brand
    6
    JAN 26, 2016 | 8:00 AM
    WEBINAR: Concordance of PTEN gene status in circulating tumor cells and tumor tissue from mCRPC patients
    WEBINAR: Concordance of PTEN gene status in circulating tumor...
    DATE: January 26th, 2016 TIME: 8am pacific, 11am eastern PTEN gene loss occurs frequently in castration-resistant prostate cancer (CRPC) and may drive progression through activation of th...
    Speaker: Edith Szafer-Glusman, PhD
    Sponsored By: Epic Sciences, Epic Sciences
    9
    SEP 16, 2014 | 10:00 AM
    Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
    Expanded clinical research opportunities for Crizotinib identified...
    Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
    Speaker: Sean Eddy, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    12
    See More
    PI3K
    Webinars
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    Virtual Events

    • JUN 02, 2021  | 5:30 AM PDT
      Immuno-Oncology Virtual Event Series 2021
      Immuno-Oncology Virtual Event Series 2021
      Labroots is pleased to announce the inauguration of the Immuno-Oncology Virtual Event Series taking place on June 2, 2021. Immuno-oncology is considered by some to be...
      45 12
      OCT 07, 2020  | 5:30 AM PDT
      Cancer Research & Oncology Week Virtual Event Series 2020
      Cancer Research & Oncology Week Virtual Event Series 2020
      LabRoots and the Cancer Research and Oncology Planning Committee are pleased to announce the 8th Annual Event in the Cancer Research & Oncology Week Virtual Event Series!...
      48 10
      SEP 30, 2020  | 5:30 AM PDT
      CRISPR Virtual Event Series 2020
      CRISPR Virtual Event Series 2020
      Labroots invites you to the 3rd Annual Event in the CRISPR Virtual Event Series! This follow up event to a very popular first-year event will continue the...
      37 3
      SEP 23, 2020  | 6:00 AM PDT
      9th Annual Fluidigm Mass Cytometry Virtual Summit
      9th Annual Fluidigm Mass Cytometry Virtual Summit
      Please join us at the 9th Annual Fluidigm Mass Cytometry Virtual Summit This yearly international meeting of the mass cytometry community is designed for new and experienced users, as well a...
      20
      MAY 19, 2020
      Advancing Science - A Virtual Oncology Conference
      Advancing Science - A Virtual Oncology Conference
      New technologies are enabling discoveries that advance our understanding of how tumors develop, evade the immune system, and progress. This virtual conference brings together research profes...
      56 12
    JUN 02, 2021  | 5:30 AM PDT
    Immuno-Oncology Virtual Event Series 2021
    Immuno-Oncology Virtual Event Series 2021
    Labroots is pleased to announce the inauguration of the Immuno-Oncology Virtual Event Series taking place on June 2, 2021. Immuno-oncology is considered by some to be...
    45 12
     
     
    OCT 07, 2020  | 5:30 AM PDT
    Cancer Research & Oncology Week Virtual Event Series 2020
    Cancer Research & Oncology Week Virtual Event Series 2020
    LabRoots and the Cancer Research and Oncology Planning Committee are pleased to announce the 8th Annual Event in the Cancer Research & Oncology Week Virtual Event Series!...
    48 10
    SEP 30, 2020  | 5:30 AM PDT
    CRISPR Virtual Event Series 2020
    CRISPR Virtual Event Series 2020
    Labroots invites you to the 3rd Annual Event in the CRISPR Virtual Event Series! This follow up event to a very popular first-year event will continue the...
    37 3
    SEP 23, 2020  | 6:00 AM PDT
    9th Annual Fluidigm Mass Cytometry Virtual Summit
    9th Annual Fluidigm Mass Cytometry Virtual Summit
    Please join us at the 9th Annual Fluidigm Mass Cytometry Virtual Summit This yearly international meeting of the mass cytometry community is designed for new and experienced users, as well a...
    20
    MAY 19, 2020
    Advancing Science - A Virtual Oncology Conference
    Advancing Science - A Virtual Oncology Conference
    New technologies are enabling discoveries that advance our understanding of how tumors develop, evade the immune system, and progress. This virtual conference brings together research profes...
    56 12
    SEP 16, 2014  | 8:00 AM PDT
    Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    Advanced Genomics in Clinical and Translational Research - Informing...
    This event will highlight the innovative use of big data to inform cancer drug development and transform cancer clinical development. The wealth of curated and well-annotated cancer genomic...
    25
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    PI3K
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